Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.40 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | PNMT | P11086 | 2/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3978179 | 1.00 | KIF11 (0.45) | KIF11ALDH1A1CYP19A1SCN5ASCN9A | |
| SCHEMBL21264407 | 1.00 | KIF11 (0.45) | KIF11ALDH1A1CYP19A1SCN5ASCN9A | |
| SCHEMBL1859294 | 0.83 | KIF11 (0.44) | KIF11ALDH1A1CYP19A1SCN5ASCN9A | |
| Hydrochloric Acid SCHEMBL16321424 | 0.81 | KIF11 (0.43) | KIF11ALDH1A1CYP19A1SCN5ASCN9A | |
| SCHEMBL3356661 | 0.80 | ALDH1A1 (0.50) | KIF11ALDH1A1CYP19A1SCN5ASCN9A | |
| SCHEMBL6074031 | 0.79 | CYP19A1 (0.47) | KIF11ALDH1A1CYP19A1SCN5ASCN9A | |
| SCHEMBL8137247 | 0.78 | ESR1 (0.50) | KIF11ALDH1A1CYP19A1SCN5ASCN9A | |
| SCHEMBL78619 | 0.78 | HDAC4 (0.47) | KIF11ALDH1A1CYP19A1SCN5ASCN9A | |
| SCHEMBL29441583 | 0.78 | HDAC4 (0.47) | KIF11ALDH1A1CYP19A1SCN5ASCN9A | |
| Hydrochloric Acid SCHEMBL27601929 | 0.78 | CYP19A1 (0.46) | KIF11ALDH1A1CYP19A1SCN5ASCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009056993-A2 | A PROCESS FOR THE SYNTHESIS OF RAMELTEON AND ITS INTERMEDIATES | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2009-05-07 | — | — | WO | claimed |
| EP-2079525-A1 | CALCIUM RECEPTOR MODULATING AGENTS | Amgen Inc. (US) | 2009-07-22 | — | — | EP | disclosed |
| WO-2009056993-A2 | A PROCESS FOR THE SYNTHESIS OF RAMELTEON AND ITS INTERMEDIATES | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2009-05-07 | — | — | WO | disclosed |
| WO-2008057282-A1 | CALCIUM RECEPTOR MODULATING AGENTS | AMGEN INC. (US) | 2008-05-15 | — | — | WO | disclosed |