Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | TP53 | P04637 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8258036 | 0.82 | SLC10A6 (0.50) | MAPTTP53ALDH1A1LMNASERPINE1 | |
| SCHEMBL18095007 | 0.81 | MAPT (0.52) | MAPTTP53ALDH1A1LMNASERPINE1 | |
| SCHEMBL19863788 | 0.80 | ALDH1A1 (0.46) | MAPTTP53ALDH1A1LMNASERPINE1 | |
| SCHEMBL29259910 | 0.79 | KDM4E (0.63) | ALDH1A1SERPINE1HSP90AA1HSP90AB1GAA | |
| SCHEMBL24269577 | 0.78 | ATR (0.53) | ALDH1A1SERPINE1HSP90AA1HSP90AB1GAA | |
| SCHEMBL19863786 | 0.78 | CCR9 (0.54) | MAPTTP53ALDH1A1LMNASERPINE1 | |
| SCHEMBL19857846 | 0.78 | CCR9 (0.57) | MAPTTP53ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL30478220 | 0.78 | HSP90AA1 (0.38) | LMNASERPINE1SMN1; SMN2HSP90AA1HSP90AB1 | |
| SCHEMBL21758801 | 0.76 | RXFP1 (0.46) | MAPTTP53ALDH1A1LMNASERPINE1 | |
| SCHEMBL3787046 | 0.76 | KMT2A (0.54) | MAPTHSP90AA1HSP90AB1GAACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12433896-B2 | Deuterated analogs of etifoxine, their derivatives and uses thereof | GABA THERAPEUTICS INC. (US) | 2025-10-07 | — | — | US | disclosed |
| US-20230263805-A1 | DEUTERATED ANALOGS OF ETIFOXINE, THEIR DERIVATIVES AND USES THEREOF | GABA THERAPEUTICS INC (US) | 2023-08-24 | — | — | US | disclosed |
| US-11672805-B2 | Deuterated analogs of etifoxine, their derivatives and uses thereof | GABA THERAPEUTICS INC. (US) | 2023-06-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12433896-B2 | Deuterated analogs of etifoxine, their derivatives and uses thereof | CYP2F1, CYP3A5, CYP4F3 | MAPT 3965/4885TP53 2248/4885ALDH1A1 1324/4885 |
| US-11672805-B2 | Deuterated analogs of etifoxine, their derivatives and uses thereof | CYP2F1, CYP3A5, CYP4F3 | MAPT 3965/4885TP53 2248/4885ALDH1A1 1324/4885 |
| US-20230263805-A1 | DEUTERATED ANALOGS OF ETIFOXINE, THEIR DERIVATIVES AND USES THEREOF | CYP2F1, CYP3A5, CYP4F3 | MAPT 3965/4885TP53 2248/4885ALDH1A1 1324/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.