SCHEMBL3047879

SCHEMBL3047879

CC(c1cnc(C(F)(F)F)nc1)S(C)(=O)=NC#N

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HDAC6 Q9UBN7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13412432 0.87 P2RX3 (0.31)
Sulfoxaflor SCHEMBL230364 0.82 LGMN (0.37)
Sulfoxaflor SCHEMBL18103858 0.82 LGMN (0.37)
Sulfoxaflor SCHEMBL17184067 0.82 LGMN (0.37)
Sulfoxaflor SCHEMBL14148160 0.82 LGMN (0.37)
Sulfoxaflor SCHEMBL29688368 0.82 LGMN (0.37)
Sulfoxaflor SCHEMBL520711 0.82 LGMN (0.37)
Sulfoxaflor SCHEMBL686361 0.82 LGMN (0.37)
Sulfoxaflor SCHEMBL18103859 0.82 LGMN (0.37)
SCHEMBL14771133 0.82 POLB (0.31) HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2328413-B1 PESTICIDAL COMPOSITIONS COMPRISING N-SUBSTITUTED SULFOXIMINES DOW AGROSCIENCES LLC (US) 2017-03-15 EP disclosed
US-20130065912-A1 PESTICIDAL COMPOSITIONS DOW AGROSCIENCES LLC (US) 2013-03-14 US disclosed
US-20130065912-A1 PESTICIDAL COMPOSITIONS DOW AGROSCIENCES LLC (US) 2013-03-14 US disclosed
US-20130065912-A1 PESTICIDAL COMPOSITIONS DOW AGROSCIENCES LLC (US) 2013-03-14 US disclosed
US-8324209-B2 Pesticidal compositions DOW AGROSCIENCES, LLC (US) 2012-12-04 US disclosed
US-8324209-B2 Pesticidal compositions DOW AGROSCIENCES, LLC (US) 2012-12-04 US disclosed
US-8324209-B2 Pesticidal compositions DOW AGROSCIENCES, LLC (US) 2012-12-04 US disclosed
WO-2010027779-A2 PESTICIDAL COMPOSITIONS DOW AGROSCIENCES LLC (US) 2010-03-11 WO disclosed
WO-2010027779-A2 PESTICIDAL COMPOSITIONS DOW AGROSCIENCES LLC (US) 2010-03-11 WO disclosed
US-20100056534-A1 PESTICIDAL COMPOSITIONS DOW AGROSCIENCES LLC (US) 2010-03-04 US disclosed
US-20100056534-A1 PESTICIDAL COMPOSITIONS DOW AGROSCIENCES LLC (US) 2010-03-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130065912-A1 PESTICIDAL COMPOSITIONS ACHE, DDT, PTMS HDAC6 2125/4885
US-20100056534-A1 PESTICIDAL COMPOSITIONS ACHE, DDT, PTMS HDAC6 2125/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.