Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.47 |
| ▸ | CASR | P41180 | 2/20 | 0.44 |
| ▸ | STAT3 | P40763 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 4/20 | 0.41 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5090323 | 1.00 | SLC7A5 (0.55) | SLC7A5RAB9ANPC1MAPTHTT | |
| SCHEMBL8176078 | 0.85 | SLC7A5 (0.51) | SLC7A5RAB9ANPC1MAPTHTT | |
| SCHEMBL17513371 | 0.83 | SLC7A5 (0.52) | SLC7A5RAB9ANPC1MAPTHTT | |
| SCHEMBL17513373 | 0.83 | SLC7A5 (0.52) | SLC7A5RAB9ANPC1MAPTHTT | |
| SCHEMBL30479003 | 0.82 | ABCG2 (0.45) | SLC7A5RAB9ANPC1MAPTHTT | |
| SCHEMBL31006729 | 0.81 | ALDH1A1 (0.53) | RAB9ANPC1MAPTSMN1; SMN2CASR | |
| SCHEMBL17785165 | 0.79 | KMT2A (0.58) | RAB9ANPC1HTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL17785164 | 0.79 | KMT2A (0.58) | RAB9ANPC1HTTSMN1; SMN2ALDH1A1 | |
| Hydrogen Peroxide SCHEMBL27146001 | 0.78 | SLC7A5 (0.60) | SLC7A5RAB9AMAPTABCB1ABCG2 | |
| SCHEMBL11453059 | 0.78 | PTGS1 (0.55) | RAB9AMAPTHTTSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116261458-B | PLK1 degradation inducing compounds | 厄普特拉株式会社 | 2024-05-24 | — | — | CN | disclosed |
| CN-116261458-A | Novel PLK1 degradation inducing compounds | 厄普特拉株式会社 | 2023-06-13 | — | — | CN | disclosed |