Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | CASR | P41180 | 1/20 | 0.51 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.50 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 6/20 | 0.49 |
| ▸ | NPC1 | O15118 | 5/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | RHOA | P61586 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MITF | O75030 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17785164 | 0.88 | KMT2A (0.58) | ALDH1A1AKR1C3AKR1C2RAB9ANPC1 | |
| SCHEMBL17785165 | 0.88 | KMT2A (0.58) | ALDH1A1AKR1C3AKR1C2RAB9ANPC1 | |
| SCHEMBL27999432 | 0.87 | PARP1 (0.50) | MEN1KMT2A | |
| SCHEMBL11453058 | 0.87 | PTGS1 (0.55) | ALDH1A1KDM4ERAB9ASMN1; SMN2MAPT | |
| SCHEMBL11453059 | 0.87 | PTGS1 (0.55) | ALDH1A1KDM4ERAB9ASMN1; SMN2MAPT | |
| SCHEMBL30607064 | 0.86 | ALDH1A1 (0.56) | ALDH1A1KDM4EAKR1C3AKR1C2RAB9A | |
| SCHEMBL9911523 | 0.86 | ALDH1A1 (0.56) | ALDH1A1KDM4EAKR1C3AKR1C2RAB9A | |
| Water SCHEMBL11454954 | 0.85 | PTGS1 (0.54) | ALDH1A1KDM4ERAB9ASMN1; SMN2MAPT | |
| Water SCHEMBL11454953 | 0.85 | PTGS1 (0.54) | ALDH1A1KDM4ERAB9ASMN1; SMN2MAPT | |
| SCHEMBL202931 | 0.84 | ITGB3 (0.51) | CASRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12059473-B2 | Humanized anti-prostate -specific membrane antigen (PSMA) antibody drug conjugates | AMBRX, INC. (US) | 2024-08-13 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12059473-B2 | Humanized anti-prostate -specific membrane antigen (PSMA) antibody drug conjugates | FOLH1, KLK3, PSMA6 | ALDH1A1 1821/4885KDM4E 709/4885CASR 1383/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.