Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.41 |
| ▸ | CHRM4 known ✓ | P08173 | 1/20 | 0.41 |
| ▸ | CHRM5 known ✓ | P08912 | 1/20 | 0.41 |
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.41 |
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.41 |
| ▸ | CCKBR | P32239 | 1/20 | 0.44 |
| ▸ | CHAT | P28329 | 1/20 | 0.43 |
| ▸ | PLK1 | P53350 | 1/20 | 0.43 |
| ▸ | TACR3 | P29371 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 4/20 | 0.41 |
| ▸ | CNR2 | P34972 | 4/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.41 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL25341697 | 0.83 | PRSS1 (0.50) | KMT2AEGFRLMNAPLA2G1BERBB2 | |
| SCHEMBL11617237 | 0.82 | PLK1 (0.48) | CCKBRPLK1TACR3KMT2AL3MBTL1 | |
| Hydrochloric Acid SCHEMBL25342080 | 0.75 | KMT2A (0.54) | KMT2AEGFRLMNAPLA2G1BERBB2 | |
| SCHEMBL5968377 | 0.73 | CCKBR (0.49) | CCKBRPLK1TACR3KMT2AL3MBTL1 | |
| SCHEMBL4313304 | 0.71 | TACR3 (0.41) | TACR3KMT2AL3MBTL1KDM4ECNR1 | |
| SCHEMBL165896 | 0.70 | PRSS1 (0.61) | CNR2TSHRALDH1A1 | |
| SCHEMBL15659861 | 0.69 | CNR2 (0.55) | KMT2AL3MBTL1KDM4ECNR1CNR2 | |
| SCHEMBL1286894 | 0.69 | NAAA (0.67) | PLK1CNR1CNR2TSHRHTT | |
| SCHEMBL15658051 | 0.69 | CNR2 (0.55) | KMT2AL3MBTL1KDM4ECNR1CNR2 | |
| SCHEMBL15660791 | 0.69 | CNR2 (0.55) | KMT2AL3MBTL1KDM4ECNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023150696-A2 | COMPOSITIONS AND METHODS FOR DELIVERING HYDROPHOBIC BIOACTIVE AGENTS | Perfect Day, Inc. (US) | 2023-08-10 | — | — | WO | disclosed |