Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 2/20 | 0.48 |
| ▸ | CHRM1 known ✓ | P11229 | 2/20 | 0.48 |
| ▸ | ACHE known ✓ | P22303 | 2/20 | 0.48 |
| ▸ | CHRM4 known ✓ | P08173 | 1/20 | 0.48 |
| ▸ | CHRM5 known ✓ | P08912 | 1/20 | 0.48 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.48 |
| ▸ | OPRM1 known ✓ | P35372 | 1/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.50 |
| ▸ | CTSG | P08311 | 2/20 | 0.50 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.50 |
| ▸ | CMA1 | P23946 | 2/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | RAD52 | P43351 | 2/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL165896 | 0.87 | PRSS1 (0.61) | PRSS1CTSGCTRB1CMA1TSHR | |
| SCHEMBL22747924 | 0.84 | PRSS1 (0.59) | PRSS1CTSGCTRB1CMA1TSHR | |
| Bromide SCHEMBL30479096 | 0.83 | CCKBR (0.44) | HSP90AA1KMT2ALMNASMN1; SMN2RAD52 | |
| Hydrochloric Acid SCHEMBL25342080 | 0.81 | KMT2A (0.54) | HSP90AA1KMT2ALMNASMN1; SMN2RAD52 | |
| SCHEMBL3693343 | 0.80 | CTRB1 (0.58) | PRSS1CTSGCTRB1CMA1HTT | |
| SCHEMBL30868632 | 0.76 | TAS1R3 (0.77) | PRSS1CTSGCTRB1CMA1LMNA | |
| SCHEMBL9067639 | 0.76 | CTSG (0.53) | PRSS1CTSGCTRB1CMA1TSHR | |
| SCHEMBL24193420 | 0.76 | TAS1R3 (0.58) | PRSS1CTSGCTRB1CMA1HTT | |
| SCHEMBL13169591 | 0.75 | TAS1R3 (0.70) | PRSS1CTSGCTRB1CMA1TAS1R3 | |
| SCHEMBL10810741 | 0.74 | PRSS1 (0.50) | PRSS1CTSGCTRB1CMA1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023150696-A2 | COMPOSITIONS AND METHODS FOR DELIVERING HYDROPHOBIC BIOACTIVE AGENTS | Perfect Day, Inc. (US) | 2023-08-10 | — | — | WO | disclosed |