Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 3/20 | 0.46 |
| ▸ | WNT1 | P04628 | 2/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | CPS1 | P31327 | 5/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | HPGDS | O60760 | 2/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30923207 | 0.85 | HTR4 (0.47) | CPS1P2RX7HPGDSNAAA | |
| SCHEMBL29535889 | 0.85 | MCHR1 (0.50) | DYRK1AWNT1MCHR1HRH3 | |
| SCHEMBL25772949 | 0.81 | DYRK1A (0.44) | DYRK1AWNT1 | |
| SCHEMBL30564259 | 0.80 | ALDH1A1 (0.56) | CNR2MCHR1 | |
| SCHEMBL2469758 | 0.79 | HPGD (0.51) | CNR2MCHR1HPGDS | |
| SCHEMBL30804736 | 0.75 | PARP1 (0.52) | CPS1P2RX7HPGDSNAAAHRH3 | |
| SCHEMBL30804723 | 0.72 | HPGDS (0.58) | MCHR1HPGDSNAAA | |
| SCHEMBL30938319 | 0.72 | HTR4 (0.50) | MCHR1HPGDSHRH3 | |
| SCHEMBL30564331 | 0.72 | DYRK1A (0.46) | DYRK1AWNT1P2RX7 | |
| SCHEMBL31438766 | 0.72 | KMT2A (0.53) | CNR2MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118574825-A | Compounds as FAK inhibitors and uses thereof | 微境生物医药科技(上海)有限公司 | 2024-08-30 | — | — | CN | disclosed |
| WO-2023160614-A1 | COMPOUND AS FAK INHIBITOR AND USE THEREOF | 微境生物医药科技(上海)有限公司 | 2023-08-31 | — | — | WO | disclosed |
| WO-2023116527-A1 | COMPOUND AS FAK INHIBITOR AND USE THEREOF | 微境生物医药科技(上海)有限公司 | 2023-06-29 | — | — | WO | disclosed |