Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 2/20 | 0.39 |
| ▸ | DRD5 | P21918 | 2/20 | 0.39 |
| ▸ | HTR2C | P28335 | 6/20 | 0.38 |
| ▸ | HTR2B | P41595 | 6/20 | 0.38 |
| ▸ | HTR2A | P28223 | 4/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8171790 | 0.78 | NPC1 (0.40) | NPC1RAB9ACYP3A4CYP2D6CYP2C9 | |
| SCHEMBL3635778 | 0.76 | MEN1 (0.42) | CYP3A4KDM1AHTR2CHTR2BHTR2A | |
| SCHEMBL133896 | 0.76 | HTR2A (0.49) | NPC1KDM1ADRD1DRD5HTR2C | |
| SCHEMBL16212102 | 0.76 | TP53 (0.47) | ALDH1A1SMN1; SMN2HTR2CHTR2BHTR2A | |
| SCHEMBL25378056 | 0.76 | HTR2C (0.49) | HTR2CHTR2BDDB1CRBN | |
| SCHEMBL16212148 | 0.76 | HTR2C (0.49) | HTR2CHTR2BDDB1CRBN | |
| SCHEMBL31227327 | 0.76 | HTR2C (0.49) | HTR2CHTR2BDDB1CRBN | |
| SCHEMBL30622726 | 0.72 | MAP1LC3B (0.40) | NPC1RAB9ACYP3A4CYP2D6CYP2C9 | |
| SCHEMBL11903532 | 0.71 | KDM4E (0.41) | NPC1CYP2D6ALDH1A1 | |
| SCHEMBL13210441 | 0.70 | DDB1 (0.57) | DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113214067-B | Preparation method of indanone compound | 长春工业大学 | 2023-06-30 | — | — | CN | claimed |
| CN-113214067-B | Preparation method of indanone compound | 长春工业大学 | 2023-06-30 | — | — | CN | disclosed |
| CN-113214067-B | Preparation method of indanone compound | 长春工业大学 | 2023-06-30 | — | — | CN | disclosed |