SCHEMBL133896

SCHEMBL133896

Brc1ccccc1C1CCc2ccccc21

nearest known ligand 0.49

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 2/20 0.49
HTR2C P28335 2/20 0.49
HTR2B P41595 2/20 0.49
HRH3 Q9Y5N1 2/20 0.49
ADRA1A P35348 1/20 0.47
IDO1 P14902 2/20 0.44
PDPK1 O15530 1/20 0.44
SIGMAR1 Q99720 1/20 0.42
DRD1 P21728 2/20 0.42
DRD5 P21918 2/20 0.42
CYP11B2 P19099 1/20 0.42
KDM1A O60341 1/20 0.41
NPC1 O15118 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28886942 0.82 ADRA1A (0.43) HTR2AADRA1AIDO1PDPK1SIGMAR1
SCHEMBL2984209 0.80 IDO1 (0.48) HTR2AADRA1AIDO1PDPK1SIGMAR1
SCHEMBL8735629 0.78 ADRA1A (0.46) ADRA1AIDO1PDPK1SIGMAR1CYP11B2
SCHEMBL1046129 0.78 PDPK1 (0.40) HTR2AHTR2CHTR2BHRH3ADRA1A
SCHEMBL30480958 0.76 NPC1 (0.43) HTR2AHTR2CHTR2BHRH3DRD1
SCHEMBL5710152 0.76 PIN1 (0.51) ADRA1AIDO1PDPK1SIGMAR1DRD1
SCHEMBL8849605 0.76 DDB1 (0.53) HTR2AHTR2CHTR2BHRH3ADRA1A
SCHEMBL78935 0.76 IDO1 (0.44) HTR2AADRA1AIDO1PDPK1SIGMAR1
SCHEMBL503849 0.75 SIGMAR1 (0.62) HTR2AHTR2CHTR2BHRH3ADRA1A
SCHEMBL29390302 0.75 SIGMAR1 (0.62) HTR2AHTR2CHTR2BHRH3ADRA1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 134 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210009778-A1 FLAME-RESISTANT FOAMED STYRENE-BASED RESIN COMPOSITION DAI-ICHI KOGYO SEIYAKU CO., LTD. (JP) 2021-01-14 US claimed
EP-3670585-A1 FLAME-RESISTANT FOAMED STYRENE-BASED RESIN COMPOSITION Dai-Ichi Kogyo Seiyaku Co., Ltd. (JP) 2020-06-24 EP claimed
CN-111032755-A Flame-retardant expandable styrene resin composition 第一工业制药株式会社 2020-04-17 CN claimed
EP-2426165-B1 FLAME-RETARDANT EXPANDABLE STYRENE RESIN COMPOSITION DAI ICHI KOGYO SEIYAKU CO LTD (JP) 2016-06-29 EP claimed
US-9187607-B2 Flame-retarded foamable styrene-based resin compositions DAI-ICHI KOGYO SEIYAKU, CO., LTD. (JP) 2015-11-17 US claimed
EP-2426152-B1 FLAME-RETARDANT EXPANDABLE STYRENE RESIN PARTICLES AND METHOD FOR PRODUCING SAME DAI ICHI KOGYO SEIYAKU CO LTD (JP) 2014-06-04 EP claimed
CN-102356096-B Flame-retardant expandable styrene resin particles and method for producing same DAI ICHI KOGYO SEIYAKU CO LTD 2014-05-21 CN claimed
CN-102356123-B Flame-retardant expandable styrene resin composition DAI ICHI KOGYO SEIYAKU CO LTD 2013-03-27 CN claimed
EP-2426152-A1 FLAME-RETARDANT EXPANDABLE STYRENE RESIN PARTICLES AND METHOD FOR PRODUCING SAME Dai-Ichi Kogyo Seiyaku Co., Ltd. (JP) 2012-03-07 EP claimed
EP-2426165-A1 FLAME-RETARDANT EXPANDABLE STYRENE RESIN COMPOSITION Dai-Ichi Kogyo Seiyaku Co., Ltd. (JP) 2012-03-07 EP claimed
CN-102356123-A Flame-retardant expandable styrene resin composition DAI ICHI KOGYO SEIYAKU CO LTD 2012-02-15 CN claimed
CN-102356096-A Flame-retardant expandable styrene resin particles and method for producing same DAI ICHI KOGYO SEIYAKU CO LTD 2012-02-15 CN claimed
US-20110319507-A1 FLAME-RETARDED FOAMABLE STYRENE-BASED RESIN BEADS AND PROCESS FOR PRODUCING THE SAME DAI-ICHI KOGYO SEIYAKU CO., LTD. (JP) 2011-12-29 US claimed
US-11970612-B2 Polyamide composition and molded product composed of said polyamide composition KURARAY CO., LTD. (JP) 2024-04-30 US disclosed
CN-115210340-B Flame retardant composition for styrene resin foam, flame retardant styrene resin foam composition, and extrusion molded foam thereof 第一工业制药株式会社 2024-04-05 CN disclosed
US-20240101807-A1 FLAME RETARDANT COMPOSITION FOR FOAMED STYRENE RESIN, FLAME-RETARDANT FOAMED STYRENE-BASED RESIN COMPOSITION, AND EXTRUSION FOAM-MOLDED PRODUCT OF SAME DKS CO. LTD. (JP) 2024-03-28 US disclosed
CN-101802049-A Epoxy resin composition for semiconductor encapsulation containing inclusion complex NIPPON SODA CO 2010-08-11 CN disclosed
US-20100179250-A1 INCLUSION COMPLEX CONTAINING EPOXY RESIN COMPOSITION FOR SEMICONDUCTOR ENCAPSULATION NIPPON SODA CO., LTD. (JP) 2010-07-15 US disclosed
EP-2192139-A1 INCLUSION COMPLEX CONTAINING EPOXY RESIN COMPOSITION FOR SEMICONDUCTOR ENCAPSULATION Nippon Soda Co., Ltd. (JP) 2010-06-02 EP disclosed
US-20060106122-A1 Extruded polystyrene resin foam board and process for preparing the same JSP CORPORATION (JP) 2006-05-18 US disclosed