Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | NAAA | Q02083 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 3/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.40 |
| ▸ | FABP4 | P15090 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methylpiperazine SCHEMBL29036019 | 1.00 | CDK1 (0.53) | CDK1TDP1NAAAPTGS1MAPK1 | |
| SCHEMBL29383677 | 0.86 | CDK1 (0.70) | CDK1TDP1NAAAPTGS1MAPK1 | |
| SCHEMBL446310 | 0.86 | CDK1 (0.70) | CDK1TDP1NAAAPTGS1MAPK1 | |
| SCHEMBL14567055 | 0.86 | CDK1 (0.70) | CDK1TDP1NAAAPTGS1MAPK1 | |
| Morpholine SCHEMBL30481045 | 0.85 | CDK1 (0.55) | CDK1TDP1NAAAPTGS1MAPK1 | |
| Thiomorpholine SCHEMBL30481039 | 0.85 | CDK1 (0.55) | CDK1TDP1NAAAPTGS1MAPK1 | |
| Morpholine SCHEMBL29036062 | 0.85 | CDK1 (0.55) | CDK1TDP1NAAAPTGS1MAPK1 | |
| Salcaprozic Acid SCHEMBL29036009 | 0.85 | NAAA (0.55) | NAAAMAPK1APP | |
| SCHEMBL5497301 | 0.84 | CDK1 (0.68) | CDK1TDP1NAAAPTGS1MAPK1 | |
| SCHEMBL2330852 | 0.84 | CDK1 (0.68) | CDK1TDP1NAAAPTGS1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116444392-B | Polypeptide protein medicine oral absorption promoter and preparation method and application thereof | 中国药科大学 | 2024-09-27 | — | — | CN | claimed |
| CN-116444392-A | Polypeptide protein medicine oral absorption promoter and preparation method and application thereof | 中国药科大学 | 2023-07-18 | — | — | CN | claimed |
| CN-116444392-B | Polypeptide protein medicine oral absorption promoter and preparation method and application thereof | 中国药科大学 | 2024-09-27 | — | — | CN | disclosed |
| CN-116444392-A | Polypeptide protein medicine oral absorption promoter and preparation method and application thereof | 中国药科大学 | 2023-07-18 | — | — | CN | disclosed |