Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | KDM4A | O75164 | 1/20 | 0.41 |
| ▸ | KDM4B | O94953 | 1/20 | 0.41 |
| ▸ | KDM5C | P41229 | 1/20 | 0.41 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.41 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25376070 | 1.00 | MEN1 (0.44) | MEN1KMT2ATDP1ALDH1A1KDM4E | |
| SCHEMBL25373983 | 0.79 | MEN1 (0.44) | MEN1KMT2ATDP1ALDH1A1BCHE | |
| SCHEMBL25375347 | 0.79 | HTR1A (0.45) | MEN1KMT2ATDP1ALDH1A1KDM4E | |
| SCHEMBL25376336 | 0.79 | KDM1A (0.54) | MEN1KMT2ATDP1ALDH1A1KDM4E | |
| SCHEMBL25376161 | 0.78 | KDM4E (0.52) | MEN1KMT2AALDH1A1KDM4ELMNA | |
| SCHEMBL31453224 | 0.77 | MAOA (0.58) | ALDH1A1LMNAMAPTTP53L3MBTL1 | |
| SCHEMBL1038941 | 0.77 | LMNA (0.65) | MEN1KMT2ATDP1ALDH1A1KDM4E | |
| SCHEMBL18843420 | 0.77 | KDM4A (0.43) | MEN1KMT2ATDP1ALDH1A1BCHE | |
| SCHEMBL19865686 | 0.77 | MCHR1 (0.39) | KDM4ELMNAMAPK1GAA | |
| SCHEMBL25380114 | 0.76 | KDM1A (0.52) | MEN1KMT2ATDP1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4469438-A1 | COMPOUNDS AND METHODS OF USE | Tango Therapeutics, Inc. (US) | 2024-12-04 | — | — | EP | disclosed |
| WO-2023146987-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |