Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH3 | Q9ULD8 | 2/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | PDE5A | O76074 | 1/20 | 0.42 |
| ▸ | GPR39 | O43194 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | GRK2 | P25098 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27829679 | 0.74 | ADRA2C (0.50) | KCNH3HDAC1HDAC6HDAC3HDAC2 | |
| SCHEMBL7132304 | 0.73 | CXCR4 (0.50) | KCNH3HDAC1HDAC6HDAC3HDAC2 | |
| SCHEMBL1308942 | 0.73 | CA12 (0.56) | KCNH3HDAC1HDAC6HDAC3HDAC2 | |
| SCHEMBL29167130 | 0.73 | CA1 (0.57) | KCNH3HDAC1HDAC6HDAC3HDAC2 | |
| SCHEMBL22191474 | 0.73 | HDAC1 (0.58) | KCNH3HDAC1HDAC6HDAC3HDAC2 | |
| SCHEMBL19242049 | 0.73 | KDM4E (0.61) | KCNH3ADRA2C | |
| SCHEMBL19241691 | 0.73 | F2 (0.56) | KCNH3HDAC1ADRA2C | |
| SCHEMBL3549143 | 0.72 | KCNH3 (0.53) | KCNH3HDAC1HDAC6HDAC3HDAC2 | |
| SCHEMBL18249767 | 0.72 | HDAC1 (0.57) | KCNH3HDAC1HDAC6HDAC3HDAC2 | |
| SCHEMBL1924273 | 0.72 | KCNH3 (1.00) | KCNH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4456900-A1 | RESPIRATORY STIMULANT PARENTERAL FORMULATIONS | Enalare Therapeutics Inc. (US) | 2024-11-06 | — | — | EP | disclosed |
| WO-2023129502-A1 | RESPIRATORY STIMULANT PARENTERAL FORMULATIONS | ENALARE THERAPEUTICS INC. (US) | 2023-07-06 | — | — | WO | disclosed |