Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2C | P18825 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | VNN1 | O95497 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KCNH3 | Q9ULD8 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | IGF1R | P08069 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | GPR39 | O43194 | 1/20 | 0.40 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30483166 | 0.74 | KCNH3 (0.56) | ADRA2CHDAC1HDAC6HDAC3HDAC2 | |
| SCHEMBL28147882 | 0.74 | MAOA (0.51) | ALDH1A1MAPTHDAC1HDAC6HDAC3 | |
| SCHEMBL22191474 | 0.73 | HDAC1 (0.58) | ADRA2CHDAC1HDAC6HDAC3HDAC2 | |
| SCHEMBL18249767 | 0.72 | HDAC1 (0.57) | ADRA2CALDH1A1HDAC1HDAC6HDAC3 | |
| SCHEMBL30395000 | 0.70 | CCNA2 (0.72) | ADRA2CCCNA2CDK2 | |
| SCHEMBL23094442 | 0.70 | HDAC1 (0.59) | ADRA2CHDAC1HDAC6HDAC3HDAC2 | |
| SCHEMBL14983698 | 0.70 | GAA (0.50) | ALDH1A1POLBKDM4EMKNK1CCNA2 | |
| SCHEMBL14983704 | 0.70 | STK17A (0.48) | — | |
| SCHEMBL21381209 | 0.69 | HDAC1 (0.58) | ADRA2CHDAC1HDAC6HDAC3HDAC2 | |
| SCHEMBL22191507 | 0.69 | RAB9A (0.56) | ALDH1A1MAPTHDAC1HDAC6HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101917981-B | Peptide deformylase inhibitors | SMITHKLINE BEECHAM CORP | 2012-11-14 | — | — | CN | disclosed |
| CN-101917981-A | Peptide deformylase inhibitors | SMITHKLINE BEECHAM CORP | 2010-12-15 | — | — | CN | disclosed |