SCHEMBL30483948

SCHEMBL30483948

C[C@H](N)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(=O)O)C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ BACE1 P56817 1/20 0.55
▸ BACE2 Q9Y5Z0 1/20 0.55
▸ OPRD1 P41143 6/20 0.55
▸ OPRM1 P35372 4/20 0.55
▸ OPRK1 P41145 1/20 0.55
▸ ENPEP Q07075 3/20 0.55
▸ MME P08473 2/20 0.51
▸ ACE P12821 2/20 0.51
▸ CASP1 P29466 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30483839 0.92 ENPEP (0.62) ENPEPMMEACE
SCHEMBL30799669 0.90 BACE1 (0.55) BACE1MMEACE
SCHEMBL30799469 0.90 MME (0.60) ENPEPMMEACE
SCHEMBL30898724 0.88 MME (0.54) OPRD1OPRM1OPRK1ENPEPMME
SCHEMBL29968694 0.88 BACE1 (0.54) BACE1BACE2OPRD1OPRM1OPRK1
SCHEMBL30799807 0.88 BACE1 (0.59) BACE1BACE2OPRD1OPRM1OPRK1
SCHEMBL2549533 0.87 MME (0.60) OPRD1OPRM1OPRK1MMEACE
SCHEMBL11799997 0.87 MME (0.56) MMEACE
SCHEMBL30445690 0.87 MME (0.60) OPRD1OPRM1OPRK1MMEACE
SCHEMBL30799883 0.87 MME (0.56) MMEACE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260130899-A1 METHOD OF TREATMENT FOR PREVENTION OF GLUCOCORTICOID TOXICITY AND/OR ENHANCEMENT OF MUSCLE REGENERATION VIA NEUTROPHIL ELASTASE INHIBITION THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2026-05-14 — — US disclosed
US-20250064792-A1 MUSCLE REGENERATION THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2025-02-27 — — US disclosed
US-20240216353-A1 METHOD OF TREATMENT FOR PREVENTION OF GLUCOCORTICOID TOXICITY AND/OR ENHANCEMENT OF MUSCLE REGENERATION VIA NEUTROPHIL ELASTASE INHIBITION THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2024-07-04 — — US disclosed
US-11918570-B2 Method of treatment for prevention of glucocorticoid toxicity and/or enhancement of muscle regeneration via neutrophil elastase inhibition THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2024-03-05 — — US disclosed
US-20230127290-A1 MUSCLE REGENERATION THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2023-04-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260130899-A1 METHOD OF TREATMENT FOR PREVENTION OF GLUCOCORTICOID TOXICITY AND/OR ENHANCEMENT OF MUSCLE REGENERATION VIA NEUTROPHIL ELASTASE INHIBITION SERPINB1, ELANE, CELA1 BACE1 508/4885BACE2 2475/4885OPRD1 2439/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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