Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 4/20 | 0.60 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.52 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.51 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.49 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.49 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.49 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 1/20 | 0.48 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.47 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | AURKA | O14965 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5351410 | 0.84 | ALDH1A1 (0.49) | SYKSCN9AMEN1KMT2ANPC1 | |
| SCHEMBL10045058 | 0.84 | CYP1A2 (0.67) | PLA2G7CYP1A2CYP1A1CYP1B1MEN1 | |
| SCHEMBL8906815 | 0.82 | PLA2G7 (0.59) | SYKPLA2G7CYP1A2CYP1A1CYP1B1 | |
| SCHEMBL3040034 | 0.81 | NPC1 (0.60) | SYKSCN9APLA2G7CSNK2A1CYP1A2 | |
| SCHEMBL722560 | 0.81 | RAB9A (0.59) | PLA2G7CSNK2A1CYP1A2KDRMEN1 | |
| Bromide SCHEMBL7502411 | 0.79 | RAB9A (0.57) | PLA2G7CSNK2A1CYP1A2KDRMEN1 | |
| Hydrochloric Acid SCHEMBL6833454 | 0.79 | RAB9A (0.57) | PLA2G7CSNK2A1CYP1A2KDRMEN1 | |
| SCHEMBL1135241 | 0.78 | ALDH1A1 (0.52) | SCN9AMEN1KMT2ANPC1RAB9A | |
| SCHEMBL12700595 | 0.77 | ALDH1A1 (0.58) | SYKKDRSIRT2SIRT1MEN1 | |
| SCHEMBL11896454 | 0.77 | PLA2G7 (0.51) | SYKPLA2G7CYP1A2CYP1A1CYP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9018209-B2 | Compounds and methods for the treatment of viruses and cancer | YALE UNIVERSITY (US) | 2015-04-28 | — | — | US | disclosed |
| US-20100222352-A1 | Compounds and Methods for the Treatment of Viruses and Cancer | YALE UNIVERSITY (US) | 2010-09-02 | — | — | US | disclosed |
| WO-2007038387-A2 | COMPOUNDS AND METHODS FOR THE TREATMENT OF VIRUSES AND CANCER | YALE UNIVERSITY (US) | 2007-04-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100222352-A1 | Compounds and Methods for the Treatment of Viruses and Cancer | RCOR1, RCOR3, CCNT1 | SYK 3473/4885SCN9A 4563/4885PLA2G7 4400/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.