SCHEMBL30484790

SCHEMBL30484790

CO[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1n1c(O)nc2c(N)ncnc21

nearest known ligand 0.61

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ HSPA8 P11142 4/20 0.61
▸ HSPA5 P11021 2/20 0.61
▸ RXFP1 Q9HBX9 1/20 0.61
▸ HSD17B10 Q99714 1/20 0.54
▸ GAPDH P04406 1/20 0.54
▸ SLC28A2 O43868 4/20 0.54
▸ LMNA P02545 1/20 0.53
▸ TP53 P04637 1/20 0.53
▸ HBB P68871 1/20 0.53
▸ SMN1; SMN2 Q16637 1/20 0.53
▸ FBP1 P09467 1/20 0.52
▸ ADORA3 P0DMS8 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23548003 0.90 HSPA8 (0.62) HSPA8HSPA5RXFP1HSD17B10GAPDH
SCHEMBL1737260 0.90 HSPA8 (0.76) HSPA8HSPA5RXFP1HSD17B10GAPDH
SCHEMBL28087475 0.90 HSPA8 (0.62) HSPA8HSPA5RXFP1HSD17B10GAPDH
SCHEMBL6388256 0.90 HSPA8 (0.62) HSPA8HSPA5RXFP1HSD17B10GAPDH
SCHEMBL31685822 0.89 MEN1 (0.48) HSPA8HSPA5RXFP1SLC28A2ADORA3
SCHEMBL30237271 0.88 HSPA8 (0.60) HSPA8HSPA5RXFP1HSD17B10GAPDH
SCHEMBL1740341 0.88 NADK (0.61) HSPA8HSPA5RXFP1HSD17B10GAPDH
SCHEMBL5672368 0.88 HSPA8 (0.60) HSPA8HSPA5RXFP1HSD17B10GAPDH
SCHEMBL30237237 0.88 NADK (0.61) HSPA8HSPA5RXFP1HSD17B10GAPDH
SCHEMBL5672193 0.88 NADK (0.61) HSPA8HSPA5RXFP1HSD17B10GAPDH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250289840-A1 RNA STABILIZING SUBSTANCES AND METHODS OF USE TEAM MEDICAL, LLC 2025-09-18 — — US disclosed
US-11680264-B2 Methods of modulating melanosome pH and melanin level in cells CORNELL UNIVERSITY (US) 2023-06-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250289840-A1 RNA STABILIZING SUBSTANCES AND METHODS OF USE SYNCRIP, SNRPA, RNASE1 HSPA8 819/4885HSPA5 393/4885RXFP1 3003/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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