Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.47 |
| ▸ | AR | P10275 | 2/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | GPR174 | Q9BXC1 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SMARCA2 | P51531 | 5/20 | 0.36 |
| ▸ | PBRM1 | Q86U86 | 5/20 | 0.36 |
| ▸ | SMARCA4 | P51532 | 4/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13419464 | 0.80 | TP53 (0.47) | ARHRH3GFERTP53MAPT | |
| SCHEMBL24478124 | 0.79 | HTR2C (0.45) | — | |
| SCHEMBL13419745 | 0.79 | GFER (0.57) | ARGFERTP53MAPTGAA | |
| SCHEMBL21593840 | 0.79 | THRB (0.41) | THRBARHRH3GFERTP53 | |
| SCHEMBL30009870 | 0.77 | MAPT (0.55) | THRBARGFERTP53MAPT | |
| SCHEMBL9983954 | 0.75 | GFER (0.63) | THRBGFERTP53MAPTGPR174 | |
| SCHEMBL8373055 | 0.74 | MAPT (0.56) | MAPTGAALMNA | |
| SCHEMBL8156058 | 0.74 | HRH3 (0.44) | THRBARHRH3 | |
| SCHEMBL2814598 | 0.74 | MAPT (0.50) | GFERMAPTGAALMNA | |
| SCHEMBL28771928 | 0.74 | GAA (0.46) | HRH3GFERMAPTGPR174GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114891003-B | Novel dihydropyrimidine compound, intermediate or salt, and preparation method and application thereof | 成都施贝康生物医药科技有限公司 | 2023-10-13 | — | — | CN | disclosed |
| CN-114656472-B | Pyrazolopyrimidine compound, isomer or salt, and preparation method and application thereof | 成都施贝康生物医药科技有限公司 | 2023-07-04 | — | — | CN | disclosed |