Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.43 |
| ▸ | GPR174 | Q9BXC1 | 3/20 | 0.42 |
| ▸ | AR | P10275 | 2/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.40 |
| ▸ | SMARCA2 | P51531 | 2/20 | 0.40 |
| ▸ | SMARCA4 | P51532 | 2/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.40 |
| ▸ | PBRM1 | Q86U86 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23043645 | 0.84 | HTT (0.55) | MAPTTP53GFERKDM4EALDH1A1 | |
| SCHEMBL29978273 | 0.84 | HTT (0.55) | MAPTTP53GFERKDM4EALDH1A1 | |
| SCHEMBL9983954 | 0.84 | GFER (0.63) | MAPTTP53GFERALDH1A1HPGD | |
| SCHEMBL13419464 | 0.81 | TP53 (0.47) | MAPTTP53GFERARNR1I2 | |
| SCHEMBL13419745 | 0.79 | GFER (0.57) | MAPTTP53GFERKDM4EALDH1A1 | |
| SCHEMBL9984458 | 0.79 | GPR174 (0.52) | MAPTTP53GFERALDH1A1KMT2A | |
| SCHEMBL30486440 | 0.77 | THRB (0.47) | MAPTTP53GFERGPR174AR | |
| SCHEMBL21593840 | 0.77 | THRB (0.41) | MAPTTP53GFERALDH1A1GPR174 | |
| SCHEMBL7087394 | 0.76 | MAPT (0.51) | MAPTTP53GFERKDM4EALDH1A1 | |
| SCHEMBL6816456 | 0.76 | MAPT (0.51) | MAPTTP53GFERKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11524968-B2 | Heterocyclic compound as a protein kinase inhibitor | HK INNO.N CORPORATION (KR) | 2022-12-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11524968-B2 | Heterocyclic compound as a protein kinase inhibitor | MAP3K20, MAP3K15, MAP3K1 | MAPT 1506/4885TP53 1110/4885GFER 4411/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.