SCHEMBL30487694

SCHEMBL30487694

Cc1ccc(C2=Cc3ccccc3C2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 3/20 0.54
CYP11B2 P19099 3/20 0.54
PTGS2 P35354 3/20 0.50
IP6K1 Q92551 1/20 0.44
IP6K3 Q96PC2 1/20 0.44
CYP19A1 P11511 1/20 0.41
DRD2 P14416 2/20 0.41
DRD4 P21917 2/20 0.41
MAOA P21397 1/20 0.37
MAOB P27338 1/20 0.37
NISCH Q9Y2I1 1/20 0.37
MTNR1A P48039 1/20 0.36
MTNR1B P49286 1/20 0.36
ACHE P22303 1/20 0.36
PRCP P42785 1/20 0.35
GPR84 Q9NQS5 1/20 0.35
NPC1 O15118 1/20 0.35
LMNA P02545 1/20 0.35
TP53 P04637 1/20 0.35
POLB P06746 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6287169 1.00 CYP11B1 (0.54) CYP11B1CYP11B2PTGS2IP6K1IP6K3
SCHEMBL8058170 0.86 CYP11B2 (0.61) CYP11B1CYP11B2PTGS2IP6K1IP6K3
SCHEMBL6285180 0.86 CYP11B2 (0.61) CYP11B1CYP11B2PTGS2IP6K1IP6K3
SCHEMBL31608568 0.85 CYP11B2 (0.65) CYP11B1CYP11B2PTGS2IP6K1IP6K3
SCHEMBL319265 0.85 CYP11B2 (0.65) CYP11B1CYP11B2PTGS2IP6K1IP6K3
SCHEMBL6280771 0.85 CYP11B1 (0.51) CYP11B1CYP11B2PTGS2IP6K1IP6K3
SCHEMBL29897853 0.85 CYP11B1 (0.51) CYP11B1CYP11B2PTGS2IP6K1IP6K3
SCHEMBL5607529 0.84 CYP11B2 (0.57) CYP11B1CYP11B2PTGS2CYP19A1MAOB
SCHEMBL31666281 0.83 CYP11B2 (0.62) CYP11B1CYP11B2PTGS2IP6K1IP6K3
SCHEMBL25358298 0.82 CYP11B2 (0.53) CYP11B1CYP11B2PTGS2IP6K1IP6K3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119824435-A Method for preparing deuterated compound through Berch-type reduction reaction under condition of no transition metal and deuterated compound obtained by method 中国科学院理化技术研究所 2025-04-15 CN disclosed
CN-116940552-A Spirocyclic hexane derivatives, pharmaceutical compositions containing them and their use as anti-apoptotic inhibitors 法国施维雅药厂 2023-10-24 CN disclosed
CN-116410237-A Synthesis method of non-bridged symmetrical metallocene catalyst, product and application thereof 中国石油天然气股份有限公司 2023-07-11 CN disclosed