Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 5/20 | 0.61 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.61 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.49 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6285180 | 1.00 | CYP11B2 (0.61) | CYP11B2CYP11B1IP6K1IP6K3PTGS2 | |
| SCHEMBL31608568 | 0.96 | CYP11B2 (0.65) | CYP11B2CYP11B1IP6K1IP6K3PTGS2 | |
| SCHEMBL319265 | 0.96 | CYP11B2 (0.65) | CYP11B2CYP11B1IP6K1IP6K3PTGS2 | |
| SCHEMBL31666281 | 0.94 | CYP11B2 (0.62) | CYP11B2CYP11B1IP6K1IP6K3PTGS2 | |
| SCHEMBL6285178 | 0.86 | CYP11B1 (0.56) | CYP11B2CYP11B1IP6K1IP6K3PTGS2 | |
| SCHEMBL6287169 | 0.86 | CYP11B1 (0.54) | CYP11B2CYP11B1IP6K1IP6K3PTGS2 | |
| SCHEMBL30487694 | 0.86 | CYP11B1 (0.54) | CYP11B2CYP11B1IP6K1IP6K3PTGS2 | |
| SCHEMBL25358298 | 0.84 | CYP11B2 (0.53) | CYP11B2CYP11B1IP6K1IP6K3PTGS2 | |
| SCHEMBL7091350 | 0.84 | CYP11B2 (0.53) | CYP11B2CYP11B1IP6K1IP6K3PTGS2 | |
| SCHEMBL7090742 | 0.84 | CYP11B1 (0.53) | CYP11B2CYP11B1IP6K1IP6K3PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6143842-A | CONTINUOUSLY TRANSFERRING POLYOLEFIN, RESIDUAL CATALYST AND UNREACTED MONOMER TO CONDITIONING ZONE OF KNOWN VOLUME AND HEATING; CONTROLLING TRANSFER/REMOVAL OF POLYOLEFIN FROM THE ZONE TO ENABLE MONOMER REMOVAL WITHOUT OVERHEATING POLYOLEFIN | HUNTSMAN POLYMERS CORPORATION (US) | 2000-11-07 | — | — | US | claimed |