Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 6/20 | 0.57 |
| ▸ | CYP11B1 | P15538 | 5/20 | 0.57 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.57 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.47 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.47 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MIF | P14174 | 1/20 | 0.36 |
| ▸ | PRCP | P42785 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5607604 | 0.85 | CYP11B2 (0.68) | CYP11B2CYP11B1CYP19A1PTGS2NISCH | |
| SCHEMBL29683776 | 0.85 | CYP11B2 (0.68) | CYP11B2CYP11B1CYP19A1PTGS2NISCH | |
| SCHEMBL6287169 | 0.84 | CYP11B1 (0.54) | CYP11B2CYP11B1CYP19A1PTGS2NISCH | |
| SCHEMBL30487694 | 0.84 | CYP11B1 (0.54) | CYP11B2CYP11B1CYP19A1PTGS2NISCH | |
| SCHEMBL11466575 | 0.82 | CYP11B2 (0.56) | CYP11B2CYP11B1CYP19A1PTGS2NISCH | |
| SCHEMBL10402898 | 0.82 | CYP11B1 (0.56) | CYP11B2CYP11B1CYP19A1PTGS2NISCH | |
| SCHEMBL11209313 | 0.82 | CYP11B1 (0.56) | CYP11B2CYP11B1CYP19A1PTGS2NISCH | |
| SCHEMBL8972556 | 0.82 | PTGS2 (0.56) | CYP11B2CYP11B1CYP19A1PTGS2NISCH | |
| SCHEMBL2627023 | 0.81 | CYP11B2 (0.54) | CYP11B2CYP11B1CYP19A1PTGS2NISCH | |
| SCHEMBL3414856 | 0.78 | CYP11B2 (0.51) | CYP11B2CYP11B1CYP19A1PTGS2NISCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1754709-A1 | Process for preparing vinylphosphates | DSM IP Assets B.V. (NL) | 2007-02-21 | — | — | EP | disclosed |
| EP-1509484-A2 | PROCESS FOR PREPARING VINYLAROMATIC COMPOUNDS | DSM IP Assets B.V. (NL) | 2005-03-02 | — | — | EP | disclosed |
| WO-2003102202-A2 | PROCESS FOR PREPARING VINYLAROMATIC COMPOUNDS | DSM IP ASSETS B.V. (NL) | 2003-12-11 | — | — | WO | disclosed |
| US-6608212-B1 | Palladium catalyzed coupling of a vinylphosphate and aryl-metal halide; preparation of such as 1-(4-(2-(pyrrolidin-n-yl)-ethoxy)phenyl)-6-methoxy-3,4-dihydronaphthalene | PFIZER, INC. | 2003-08-19 | — | — | US | disclosed |