Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 7/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | AGXT | P21549 | 4/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL649159 | 0.95 | TSHR (0.46) | TSHRIDO1SMN1; SMN2AGXTMRGPRX4 | |
| SCHEMBL13274041 | 0.89 | SOD1 (0.42) | TSHRIDO1SMN1; SMN2KDM4EAGXT | |
| SCHEMBL14962810 | 0.87 | IDO1 (0.40) | TSHRIDO1SMN1; SMN2AGXTMRGPRX4 | |
| SCHEMBL18949771 | 0.85 | ALDH1A1 (0.39) | TSHRIDO1SMN1; SMN2AGXTMRGPRX4 | |
| SCHEMBL17214615 | 0.85 | ENPP2 (0.50) | IDO1SMN1; SMN2MRGPRX4NFKB1MAOB | |
| SCHEMBL20547932 | 0.85 | MRGPRX4 (0.46) | TSHRIDO1SMN1; SMN2MRGPRX4TP53 | |
| SCHEMBL133476 | 0.85 | TSHR (0.48) | TSHRIDO1KCNH2KDM4EAGXT | |
| SCHEMBL29928701 | 0.85 | MRGPRX4 (0.46) | TSHRIDO1SMN1; SMN2MRGPRX4TP53 | |
| SCHEMBL16478 | 0.83 | TSHR (0.70) | TSHRIDO1SMN1; SMN2KDM4EAGXT | |
| SCHEMBL8750524 | 0.83 | IDO1 (0.62) | IDO1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5145949-A | Production process for making aromatic amine resins | MITSUI TOATSU CHEMICALS, INC. (JP) | 1992-09-08 | — | — | US | disclosed |
| US-5106953-A | Reacting aromatic amines with bishalogenomethyl derivatives; curing agents or raw materials for polyamides | MITSUI TOATSU CHEMICALS, INC. (JP) | 1992-04-21 | — | — | US | disclosed |