Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.44 |
| ▸ | MEN1 | O00255 | 6/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 8/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | CASP1 | P29466 | 4/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | SNCA | P37840 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25275172 | 0.80 | RAPGEF3 (0.36) | KMT2AMEN1GAASMN1; SMN2TSHR | |
| SCHEMBL14342737 | 0.73 | KMT2A (0.50) | KMT2AMEN1GAASMN1; SMN2TSHR | |
| SCHEMBL21503683 | 0.70 | SLC2A1 (0.37) | ALDH1A1HDAC3HDAC1HDAC2KDM4E | |
| SCHEMBL30488185 | 0.70 | SCN10A (0.42) | HDAC3HDAC1HDAC2CYP2C9ALOX5 | |
| SCHEMBL29834165 | 0.70 | MEN1 (0.41) | KMT2AMEN1GAASMN1; SMN2TSHR | |
| SCHEMBL26773895 | 0.68 | SCN10A (0.39) | TSHRL3MBTL1 | |
| SCHEMBL19466194 | 0.68 | ALDH1A1 (0.41) | KMT2AMEN1GAATSHRMAPT | |
| SCHEMBL23651744 | 0.68 | TSHR (0.42) | KMT2AMEN1GAASMN1; SMN2TSHR | |
| SCHEMBL20098206 | 0.68 | SCN10A (0.41) | TSHRL3MBTL1CYP1A2 | |
| SCHEMBL20372909 | 0.67 | ESR1 (0.36) | L3MBTL1CYP1A2ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107630-A2 | AMINO ALCOHOL COMPOUNDS AND USES THEREOF | Kineta, Inc. (US) | 2023-06-15 | — | — | WO | disclosed |