Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | BCR | P11274 | 1/20 | 0.38 |
| ▸ | PLA2G10 | O15496 | 3/20 | 0.37 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.37 |
| ▸ | PLA2G5 | P39877 | 3/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | PDE2A | O00408 | 3/20 | 0.36 |
| ▸ | FPR2 | P25090 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CFTR | P13569 | 1/20 | 0.36 |
| ▸ | CPB1 | P15086 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26773895 | 0.78 | SCN10A (0.39) | SCN10AABL1BCRPDE2A | |
| SCHEMBL20372909 | 0.77 | ESR1 (0.36) | SCN10AABL1BCRPDE2ANOS3 | |
| SCHEMBL1849854 | 0.76 | ADRA2A (0.38) | HDAC1HDAC2NOS3NOS2CYP2C9 | |
| SCHEMBL21503683 | 0.72 | SLC2A1 (0.37) | SCN10AABL1BCRHDAC3HDAC1 | |
| SCHEMBL934355 | 0.72 | EPHX1 (0.52) | SCN10AEPHX1HDAC3HDAC1HDAC2 | |
| SCHEMBL20098206 | 0.72 | SCN10A (0.41) | SCN10APDE2AHRH3PDE3APDE10A | |
| SCHEMBL21600629 | 0.71 | SCN10A (0.46) | SCN10APDE2ASCN9A | |
| SCHEMBL13073830 | 0.71 | SCN10A (0.41) | SCN10APDE2ASCN9A | |
| SCHEMBL30488161 | 0.70 | KMT2A (0.44) | HDAC3HDAC1HDAC2CYP2C9ALOX5 | |
| SCHEMBL11501021 | 0.70 | ALDH1A1 (0.44) | EPHX1HDAC3HDAC1HDAC2PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107630-A2 | AMINO ALCOHOL COMPOUNDS AND USES THEREOF | Kineta, Inc. (US) | 2023-06-15 | — | — | WO | disclosed |