SCHEMBL26291337

SCHEMBL26291337

OCc1ccc(OC(F)F)c(C(F)(F)F)c1

nearest known ligand 0.44

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
RXRA P19793 3/20 0.44
RXRB P28702 3/20 0.44
RXRG P48443 3/20 0.44
KIF11 P52732 1/20 0.41
PDE4A P27815 2/20 0.41
S1PR1 P21453 5/20 0.40
AR P10275 1/20 0.40
PPARG P37231 1/20 0.36
TTR P02766 1/20 0.36
USP28 Q96RU2 1/20 0.35
USP25 Q9UHP3 1/20 0.35
IDO1 P14902 2/20 0.35
PDE4B Q07343 1/20 0.35
PDE4C Q08493 1/20 0.35
PDE4D Q08499 1/20 0.35
CYP4F2 P78329 1/20 0.34
CYP4A11 Q02928 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30488261 0.85 RXRA (0.59) RXRARXRBRXRGKIF11S1PR1
SCHEMBL2019451 0.85 RXRA (0.59) RXRARXRBRXRGKIF11S1PR1
SCHEMBL10088920 0.84 RXRA (0.42) RXRARXRBRXRGKIF11S1PR1
SCHEMBL23032636 0.83 RXRA (0.44) RXRARXRBRXRGPDE4AS1PR1
SCHEMBL26291332 0.83 RXRA (0.41) RXRARXRBRXRGPDE4AS1PR1
SCHEMBL2328507 0.83 RXRA (0.47) RXRARXRBRXRGKIF11S1PR1
SCHEMBL7418541 0.80 PDE4A (0.52) PDE4ATTRPDE4BPDE4CPDE4D
SCHEMBL1437536 0.79 S1PR1 (0.58) RXRARXRBRXRGKIF11S1PR1
SCHEMBL31435356 0.79 S1PR1 (0.58) RXRARXRBRXRGKIF11S1PR1
SCHEMBL10088933 0.78 S1PR1 (0.44) RXRARXRBRXRGKIF11S1PR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230295076-A1 ACETOPHENONE OXIME COMPOUND AND APPLICATION THEREOF MEDSHINE DISCOVERY INC. (CN) 2023-09-21 US disclosed
US-20230295076-A1 ACETOPHENONE OXIME COMPOUND AND APPLICATION THEREOF MEDSHINE DISCOVERY INC. (CN) 2023-09-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230295076-A1 ACETOPHENONE OXIME COMPOUND AND APPLICATION THEREOF CYP11B2, ALDH7A1, CYP11B1 RXRA 2685/4885RXRB 2004/4885RXRG 2880/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.