Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | NSD2 | O96028 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.42 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.42 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | GABRP | O00591 | 1/20 | 0.40 |
| ▸ | GABRD | O14764 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5364336 | 1.00 | GRM5 (0.43) | GRM5ELANEL3MBTL1NSD2ABL1 | |
| SCHEMBL9375957 | 0.77 | S1PR1 (0.36) | ELANEGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL29642309 | 0.76 | NSD2 (0.43) | GRM5ELANEL3MBTL1NSD2ABL1 | |
| SCHEMBL4978551 | 0.76 | NSD2 (0.43) | GRM5ELANEL3MBTL1NSD2ABL1 | |
| SCHEMBL29424829 | 0.75 | CDK2 (0.49) | GRM5LOXL2GABRPGABRDGABRA1 | |
| SCHEMBL22533985 | 0.75 | CDK2 (0.49) | GRM5LOXL2GABRPGABRDGABRA1 | |
| SCHEMBL1010648 | 0.75 | MEN1 (0.53) | GRM5ELANEL3MBTL1PKMPDE10A | |
| SCHEMBL9376060 | 0.74 | MAPT (0.42) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL2879587 | 0.74 | L3MBTL1 (0.51) | GRM5ELANEL3MBTL1NSD2ABL1 | |
| SCHEMBL28482667 | 0.74 | GABRG2 (0.52) | ELANEL3MBTL1NSD2ABL1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250051276-A1 | ARYLOXY PSYCHOPLASTOGENS AND USES THEREOF | DELIX THERAPEUTICS, INC. | 2025-02-13 | — | — | US | disclosed |
| WO-2023114238-A1 | ARYLOXY PSYCHOPLASTOGENS AND USES THEREOF | DELIX THERAPEUTICS, INC. (US) | 2023-06-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250051276-A1 | ARYLOXY PSYCHOPLASTOGENS AND USES THEREOF | GRIN2A, GRIN2C, GAP43 | GRM5 41/4885ELANE 4565/4885L3MBTL1 3104/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.