Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH3 | Q9ULD8 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.42 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25302749 | 1.00 | KCNH3 (0.50) | KCNH3ALDH1A1HPGDMAPK1KDM4E | |
| SCHEMBL25302746 | 1.00 | KCNH3 (0.50) | KCNH3ALDH1A1HPGDMAPK1KDM4E | |
| SCHEMBL12523516 | 0.78 | ALDH1A1 (0.55) | KCNH3ALDH1A1HPGDMAPK1KDM4E | |
| SCHEMBL29326197 | 0.77 | VCP (0.41) | MAPK1KDM4E | |
| SCHEMBL25294696 | 0.75 | ALDH1A1 (0.51) | KCNH3ALDH1A1HPGDMAPK1KDM4E | |
| SCHEMBL25294695 | 0.75 | ALDH1A1 (0.51) | KCNH3ALDH1A1HPGDMAPK1KDM4E | |
| SCHEMBL29325857 | 0.75 | ALDH1A1 (0.51) | KCNH3ALDH1A1HPGDMAPK1KDM4E | |
| Water SCHEMBL4690707 | 0.73 | KCNH3 (0.57) | KCNH3ALDH1A1HPGDMAPK1KDM4E | |
| SCHEMBL30181846 | 0.72 | ALDH1A1 (0.52) | KCNH3ALDH1A1HPGDMAPK1KDM4E | |
| SCHEMBL29326005 | 0.71 | ALDH1A1 (0.47) | KCNH3ALDH1A1HPGDMAPK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119798221-A | NLRP3 inflammation corpuscle inhibitor and application thereof | 药捷安康(南京)科技股份有限公司 | 2025-04-11 | — | — | CN | disclosed |
| CN-116410140-A | NLRP3 inflammation corpuscle inhibitor and application thereof | 药捷安康(南京)科技股份有限公司 | 2023-07-11 | — | — | CN | disclosed |