Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 8/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.48 |
| ▸ | GAA | P10253 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | GBA1 | P04062 | 1/20 | 0.44 |
| ▸ | PDE5A | O76074 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25302500 | 1.00 | NLRP3 (0.57) | NLRP3MAPTMAPK1GAALMNA | |
| SCHEMBL30488484 | 0.87 | NLRP3 (0.46) | NLRP3MAPTMAPK1GAALMNA | |
| SCHEMBL25300770 | 0.87 | NLRP3 (0.46) | NLRP3MAPTMAPK1GAALMNA | |
| SCHEMBL25860642 | 0.83 | NLRP3 (0.50) | NLRP3MAPTMAPK1GAALMNA | |
| SCHEMBL25856345 | 0.79 | TNK2 (0.41) | MAPTMAPK1GAALMNAALDH1A1 | |
| SCHEMBL30488545 | 0.79 | TNK2 (0.41) | MAPTMAPK1GAALMNAALDH1A1 | |
| SCHEMBL29030601 | 0.79 | TNK2 (0.41) | MAPTMAPK1GAALMNAALDH1A1 | |
| SCHEMBL25862365 | 0.79 | TNK2 (0.41) | MAPTMAPK1GAALMNAALDH1A1 | |
| SCHEMBL30488495 | 0.79 | TNK2 (0.41) | MAPTMAPK1GAALMNAALDH1A1 | |
| SCHEMBL25302310 | 0.78 | KDM4E (0.41) | NLRP3MAPK1GAALMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119798221-A | NLRP3 inflammation corpuscle inhibitor and application thereof | 药捷安康(南京)科技股份有限公司 | 2025-04-11 | — | — | CN | disclosed |
| CN-116410140-A | NLRP3 inflammation corpuscle inhibitor and application thereof | 药捷安康(南京)科技股份有限公司 | 2023-07-11 | — | — | CN | disclosed |