Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR3 | Q99500 | 4/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.38 |
| ▸ | FFAR2 | O15552 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18322302 | 1.00 | S1PR3 (0.42) | S1PR3S1PR1LMNACYP19A1FFAR2 | |
| SCHEMBL22776044 | 0.83 | TRPM8 (0.38) | LMNATRPM8 | |
| SCHEMBL21831285 | 0.80 | S1PR3 (0.40) | S1PR3S1PR1LMNACYP19A1FFAR2 | |
| SCHEMBL30489100 | 0.77 | CYP19A1 (0.38) | S1PR3S1PR1LMNACYP19A1FFAR2 | |
| SCHEMBL4707557 | 0.77 | CYP19A1 (0.38) | S1PR3S1PR1LMNACYP19A1FFAR2 | |
| SCHEMBL11711228 | 0.74 | MEN1 (0.51) | LMNAALDH1A1MAPT | |
| SCHEMBL4182229 | 0.72 | FAAH (0.43) | LMNAALDH1A1MAPT | |
| SCHEMBL30986731 | 0.72 | TSHR (0.42) | LMNAHPGDALDH1A1MAPT | |
| SCHEMBL5377768 | 0.72 | TSHR (0.42) | LMNAHPGDALDH1A1MAPT | |
| SCHEMBL30802067 | 0.72 | TSHR (0.42) | LMNAHPGDALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107787322-B | Tricyclic compounds and their use as phosphodiesterase inhibitors | 辉瑞大药厂 | 2023-07-07 | — | — | CN | disclosed |