Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 16/20 | 0.51 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | ACVR1B | P36896 | 3/20 | 0.37 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.37 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30490066 | 0.88 | TYK2 (0.41) | TYK2ACVR1BTGFBR1ACVRL1 | |
| SCHEMBL30724634 | 0.85 | TYK2 (0.49) | TYK2JAK1JAK2 | |
| SCHEMBL24498436 | 0.85 | TYK2 (0.56) | TYK2JAK1JAK2 | |
| SCHEMBL29686099 | 0.85 | TYK2 (0.56) | TYK2JAK1JAK2 | |
| SCHEMBL30490068 | 0.85 | TYK2 (0.46) | TYK2JAK1JAK2 | |
| SCHEMBL30490080 | 0.82 | TYK2 (0.49) | TYK2JAK1 | |
| SCHEMBL30490253 | 0.81 | TYK2 (0.47) | TYK2JAK1JAK2 | |
| SCHEMBL24498345 | 0.81 | TYK2 (0.58) | TYK2JAK1JAK2 | |
| SCHEMBL30490252 | 0.80 | JAK2 (0.55) | TYK2JAK1JAK2 | |
| SCHEMBL24498480 | 0.80 | TYK2 (0.63) | TYK2JAK1JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116283954-A | Hydroxamate compound, preparation method and application thereof | 深圳微芯生物科技股份有限公司 | 2023-06-23 | — | — | CN | claimed |
| CN-116283954-A | Hydroxamate compound, preparation method and application thereof | 深圳微芯生物科技股份有限公司 | 2023-06-23 | — | — | CN | disclosed |