Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GGPS1 | O95749 | 8/20 | 0.48 |
| ▸ | FDPS | P14324 | 18/20 | 0.48 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24616673 | 0.73 | FDPS (0.68) | GGPS1FDPSPDE3ALMNAADRB3 | |
| SCHEMBL24616672 | 0.73 | FDPS (0.52) | GGPS1FDPSPDE3ALMNAADRB3 | |
| SCHEMBL2702334 | 0.71 | FDPS (0.50) | GGPS1FDPSPDE3ALMNAADRB3 | |
| SCHEMBL7762827 | 0.71 | FDPS (0.61) | GGPS1FDPSPDE3ALMNAADRB3 | |
| SCHEMBL4906431 | 0.69 | FDPS (0.42) | GGPS1FDPSPDE3ALMNAADRB3 | |
| SCHEMBL11498890 | 0.69 | FDPS (0.42) | GGPS1FDPSPDE3ALMNAADRB3 | |
| SCHEMBL15411105 | 0.69 | FDPS (0.48) | GGPS1FDPSPDE3ALMNAADRB3 | |
| SCHEMBL6667332 | 0.69 | FDPS (0.48) | GGPS1FDPSPDE3ALMNAADRB3 | |
| SCHEMBL3144201 | 0.69 | FDPS (0.48) | GGPS1FDPSPDE3ALMNAADRB3 | |
| SCHEMBL2152289 | 0.69 | FDPS (0.48) | GGPS1FDPSPDE3ALMNAADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010116132-A2 | BISPHOSPHONATE COMPOUNDS FOR CHELATING RADIONUCLIDES | KING'S COLLEGE LONDON (GB) | 2010-10-14 | — | — | WO | disclosed |