Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 19/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | GGPS1 | O95749 | 8/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3049013 | 0.69 | GGPS1 (0.48) | FDPSPDE3ALMNAADRB3PDE4D | |
| SCHEMBL6665191 | 0.69 | FDPS (0.48) | FDPSPDE3ALMNAADRB3PDE4D | |
| SCHEMBL24616673 | 0.67 | FDPS (0.68) | FDPSPDE3ALMNAADRB3PDE4D | |
| SCHEMBL24616672 | 0.67 | FDPS (0.52) | FDPSPDE3ALMNAADRB3PDE4D | |
| SCHEMBL6669718 | 0.67 | FDPS (0.46) | FDPSPDE3ALMNAADRB3PDE4D | |
| SCHEMBL2702334 | 0.65 | FDPS (0.50) | FDPSPDE3ALMNAADRB3PDE4D | |
| SCHEMBL9614498 | 0.65 | FDPS (0.39) | FDPSPDE3ALMNAADRB3PDE4D | |
| SCHEMBL11498890 | 0.63 | FDPS (0.42) | FDPSPDE3ALMNAADRB3PDE4D | |
| SCHEMBL6667332 | 0.63 | FDPS (0.48) | FDPSPDE3ALMNAADRB3PDE4D | |
| SCHEMBL15411105 | 0.63 | FDPS (0.48) | FDPSPDE3ALMNAADRB3PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080200679-A1 | Alpha-HYDROXY, alpha-SUBSTITUTED METHYLENEBISPHOSPHONATES AND PHOSPHONOACETATES | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2008-08-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080200679-A1 | Alpha-HYDROXY, alpha-SUBSTITUTED METHYLENEBISPHOSPHONATES AND PHOSPHONOACETATES | GRHPR, PHPT1, PHYKPL | FDPS 284/4885PDE3A 2692/4885LMNA 3681/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.