Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLCG1 | P19174 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6702524 | 1.00 | PLCG1 (0.35) | PLCG1ADORA3CYP3A4MAPK1ALDH1A1 | |
| SCHEMBL6702522 | 1.00 | PLCG1 (0.35) | PLCG1ADORA3CYP3A4MAPK1ALDH1A1 | |
| SCHEMBL3033995 | 0.90 | PLCG1 (0.36) | PLCG1ADORA3CYP3A4ALDH1A1KMT2A | |
| SCHEMBL6702237 | 0.90 | PLCG1 (0.36) | PLCG1ADORA3CYP3A4ALDH1A1KMT2A | |
| SCHEMBL6702233 | 0.90 | PLCG1 (0.36) | PLCG1ADORA3CYP3A4ALDH1A1KMT2A | |
| SCHEMBL3048174 | 0.88 | POLB (0.32) | PLCG1ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL6703665 | 0.88 | POLB (0.32) | PLCG1ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL6703668 | 0.88 | POLB (0.32) | PLCG1ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL3037698 | 0.84 | PLCG1 (0.35) | PLCG1CYP3A4ALDH1A1RAB9ACYP1A2 | |
| SCHEMBL3588572 | 0.84 | PLCG1 (0.35) | PLCG1CYP3A4ALDH1A1RAB9ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1499620-B1 | PROCESS FOR PREPARING 6-ALKYLIDENE PENEM DERIVATIVES | WYETH CORP (US) | 2010-01-27 | — | — | EP | disclosed |
| US-20040132708-A1 | Process for preparing 6-alkylidene penem derivatives | WYETH | 2004-07-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040132708-A1 | Process for preparing 6-alkylidene penem derivatives | PGM2, BPGM, MRPL21 | PLCG1 3678/4885ADORA3 4105/4885CYP3A4 255/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.