Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6703668 | 1.00 | POLB (0.32) | POLBSMN1; SMN2L3MBTL1ALDH1A1PLCG1 | |
| SCHEMBL3048174 | 1.00 | POLB (0.32) | POLBSMN1; SMN2L3MBTL1ALDH1A1PLCG1 | |
| SCHEMBL3046825 | 0.92 | POLB (0.32) | POLBSMN1; SMN2L3MBTL1ALDH1A1PLCG1 | |
| SCHEMBL6268828 | 0.92 | POLB (0.32) | POLBSMN1; SMN2L3MBTL1ALDH1A1PLCG1 | |
| SCHEMBL6701541 | 0.92 | POLB (0.32) | POLBSMN1; SMN2L3MBTL1ALDH1A1PLCG1 | |
| SCHEMBL6701542 | 0.92 | POLB (0.32) | POLBSMN1; SMN2L3MBTL1ALDH1A1PLCG1 | |
| SCHEMBL6702522 | 0.88 | PLCG1 (0.35) | POLBSMN1; SMN2ALDH1A1PLCG1 | |
| SCHEMBL3049029 | 0.88 | PLCG1 (0.35) | POLBSMN1; SMN2ALDH1A1PLCG1 | |
| SCHEMBL6702524 | 0.88 | PLCG1 (0.35) | POLBSMN1; SMN2ALDH1A1PLCG1 | |
| SCHEMBL3033995 | 0.84 | PLCG1 (0.36) | ALDH1A1PLCG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040053913-A1 | Process for preparing 6-alkylidene penem derivatives | WYETH | 2004-03-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040053913-A1 | Process for preparing 6-alkylidene penem derivatives | PGM2, BPGM, MRPL21 | POLB 338/4885SMN1; SMN2 1450/4885L3MBTL1 2964/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.