SCHEMBL30490487

SCHEMBL30490487

CCC(C)(Oc1ccc(Cl)cc1Cl)C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.50
TSHR P16473 3/20 0.49
MRGPRX4 Q96LA9 3/20 0.47
TTR P02766 2/20 0.46
SMN1; SMN2 Q16637 3/20 0.45
HPGD P15428 3/20 0.44
NPC1 O15118 2/20 0.44
RAB9A P51151 2/20 0.44
ALDH1A1 P00352 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
PPARG P37231 1/20 0.43
PPARA Q07869 1/20 0.43
MAPT P10636 1/20 0.43
CYP1A2 P05177 2/20 0.43
CYP2C19 P33261 2/20 0.43
CYP2C9 P11712 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21056074 0.87 TSHR (0.49) TDP1TSHRMRGPRX4SMN1; SMN2HPGD
SCHEMBL11465749 0.86 FFAR1 (0.54) TDP1MRGPRX4TTRPPARGPPARA
SCHEMBL10874937 0.83 TDP1 (0.51) TDP1TSHRMRGPRX4TTRSMN1; SMN2
SCHEMBL2558112 0.83 FBP1 (0.44) TSHRTTRALDH1A1L3MBTL1CYP1A2
SCHEMBL581884 0.81 PPARA (0.59) TDP1TSHRMRGPRX4TTRSMN1; SMN2
SCHEMBL10720195 0.79 MRGPRX4 (0.40) TDP1TSHRMRGPRX4TTRSMN1; SMN2
SCHEMBL29964312 0.78 TDP1 (0.47) TDP1TSHRMRGPRX4TTRSMN1; SMN2
SCHEMBL10344600 0.78 TDP1 (0.49) TDP1TSHRMRGPRX4TTRSMN1; SMN2
SCHEMBL27868402 0.78 HTR2C (0.43) PPARGPPARA
SCHEMBL3500736 0.78 PPARA (0.68) TDP1TSHRSMN1; SMN2HPGDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116621697-A Preparation method of dextrorotation 2- (2, 4-dichlorophenoxy) propionic acid 南京工业大学 2023-08-22 CN disclosed