Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.54 |
| ▸ | PPARA | Q07869 | 7/20 | 0.50 |
| ▸ | PPARG | P37231 | 5/20 | 0.50 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.50 |
| ▸ | TTR | P02766 | 2/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | PPARD | Q03181 | 2/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | FABP2 | P12104 | 1/20 | 0.44 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30490487 | 0.86 | TDP1 (0.50) | PPARAPPARGMRGPRX4TTRCYP1A2 | |
| SCHEMBL987343 | 0.84 | PPARA (0.67) | FFAR1PPARAPPARGMRGPRX4TTR | |
| SCHEMBL3500736 | 0.83 | PPARA (0.68) | PPARAPPARGADORA3PPARDOPRK1 | |
| SCHEMBL11548490 | 0.80 | ADORA3 (0.61) | PPARAPPARGADORA3OPRK1MEN1 | |
| 2,4-Dichlorophenoxyacetic Acid SCHEMBL9376023 | 0.78 | TDP1 (0.63) | FFAR1PPARAPPARGPPARDMEN1 | |
| SCHEMBL9385278 | 0.78 | FFAR1 (0.50) | FFAR1MRGPRX4TTRADORA3MEN1 | |
| SCHEMBL11073216 | 0.77 | OPRK1 (0.73) | PPARAPPARGADORA3PPARDOPRK1 | |
| SCHEMBL21056074 | 0.77 | TSHR (0.49) | PPARAPPARGMRGPRX4PPARDOPRK1 | |
| SCHEMBL10942708 | 0.76 | PPARG (0.44) | PPARAPPARGADORA3OPRK1MEN1 | |
| SCHEMBL28275130 | 0.76 | MRGPRX4 (0.70) | FFAR1MRGPRX4TTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4231787-A | 4-(TRIFLUOROMETHYLPHENOXY)PHENOXY-PROPANOLS OR ESTERS | ISHIHARA SANGYO KAISHA LTD. (JP) | 1980-11-04 | — | — | US | disclosed |
| US-4105435-A | 4-(3,5-DIHALO- OR 5-HALOPYRIDYL-2-OXY)PHENOXY PROPANES | ISHIHARA SANGYO KAISHA LTD. (JP) | 1978-08-08 | — | — | US | disclosed |