Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHA2 | P29317 | 2/20 | 0.39 |
| ▸ | ACE | P12821 | 3/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 7/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.37 |
| ▸ | NTSR2 | O95665 | 2/20 | 0.37 |
| ▸ | NTSR1 | P30989 | 2/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | KDM5A | P29375 | 1/20 | 0.37 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.37 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30173901 | 0.89 | ACE (0.44) | EPHA2ACEOPRK1OPRM1KDM1A | |
| SCHEMBL30490593 | 0.87 | OPRK1 (0.45) | EPHA2ACEOPRK1OPRM1NTSR2 | |
| SCHEMBL9551335 | 0.86 | EPHA2 (0.46) | EPHA2ACEOPRK1OPRM1KDM1A | |
| SCHEMBL30552516 | 0.84 | ACE (0.49) | ACEOPRK1OPRM1NTSR2NTSR1 | |
| SCHEMBL30173928 | 0.84 | EPHA2 (0.45) | EPHA2OPRK1OPRM1NTSR2NTSR1 | |
| SCHEMBL29802056 | 0.83 | OPRK1 (0.46) | ACEOPRK1OPRM1 | |
| SCHEMBL29802045 | 0.83 | OPRK1 (0.49) | ACEOPRK1OPRM1NTSR2NTSR1 | |
| SCHEMBL30422984 | 0.83 | ACE (0.47) | ACEOPRK1OPRM1NTSR2NTSR1 | |
| SCHEMBL30443975 | 0.82 | ACE (0.45) | EPHA2ACEKDM1AMAOBKDM5A | |
| SCHEMBL30490581 | 0.81 | ACE (0.41) | ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4214221-A1 | ANTIMICROBIAL PEPTIDOMIMETICS | Spexis AG (CH) | 2023-07-26 | — | — | EP | claimed |
| EP-4214221-A1 | ANTIMICROBIAL PEPTIDOMIMETICS | Spexis AG (CH) | 2023-07-26 | — | — | EP | disclosed |