Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KHK | P50053 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TYMS | P04818 | 2/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 4/20 | 0.41 |
| ▸ | MMP9 | P14780 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25321380 | 1.00 | MAPT (0.48) | MAPTMEN1KMT2APOLBPABPC1 | |
| SCHEMBL22912818 | 0.88 | KDM4E (0.62) | MAPTMEN1KMT2APOLBPABPC1 | |
| SCHEMBL29396688 | 0.88 | KDM4E (0.62) | MAPTMEN1KMT2APOLBPABPC1 | |
| SCHEMBL29397055 | 0.82 | PARP1 (0.48) | MAPTMEN1KMT2APOLBPABPC1 | |
| SCHEMBL28686826 | 0.82 | PARP1 (0.48) | MAPTMEN1KMT2APOLBPABPC1 | |
| SCHEMBL25912269 | 0.80 | MAPT (0.46) | MAPTMEN1KMT2APOLBPABPC1 | |
| SCHEMBL29396402 | 0.79 | PARP1 (0.50) | MAPTMEN1KMT2APOLBPABPC1 | |
| SCHEMBL24282029 | 0.79 | PARP1 (0.50) | MAPTMEN1KMT2APOLBPABPC1 | |
| SCHEMBL29790297 | 0.78 | KDM4E (0.76) | MAPTMEN1KMT2APOLBPABPC1 | |
| SCHEMBL14474322 | 0.76 | ALDH1A1 (0.54) | MAPTMEN1KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116425744-A | Piperazine-containing ring derivative, pharmaceutically acceptable salt thereof, and preparation method and application thereof | 优领医药科技(香港)有限公司 | 2023-07-14 | — | — | CN | disclosed |