Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | KHK | P50053 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TYMS | P04818 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TNKS | O95271 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | PARP6 | Q2NL67 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30493593 | 0.80 | MAPT (0.48) | MAPTMEN1POLBPABPC1KMT2A | |
| SCHEMBL25321380 | 0.80 | MAPT (0.48) | MAPTMEN1POLBPABPC1KMT2A | |
| SCHEMBL29396402 | 0.77 | PARP1 (0.50) | MAPTMEN1POLBPABPC1KMT2A | |
| SCHEMBL29397055 | 0.77 | PARP1 (0.48) | MAPTMEN1POLBPABPC1KMT2A | |
| SCHEMBL24282029 | 0.77 | PARP1 (0.50) | MAPTMEN1POLBPABPC1KMT2A | |
| SCHEMBL28686826 | 0.77 | PARP1 (0.48) | MAPTMEN1POLBPABPC1KMT2A | |
| SCHEMBL29790297 | 0.76 | KDM4E (0.76) | MAPTMEN1POLBPABPC1KMT2A | |
| SCHEMBL23717308 | 0.75 | ALDH1A1 (0.77) | MAPTPOLBALDH1A1KDM4EHPGD | |
| SCHEMBL22963739 | 0.74 | HTT (0.65) | MAPTMEN1POLBPABPC1KMT2A | |
| SCHEMBL29396650 | 0.74 | HTT (0.65) | MAPTMEN1POLBPABPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023134647-A1 | PIPERAZINO RING-CONTAINING DERIVATIVE, PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | 优领医药科技(香港)有限公司 | 2023-07-20 | — | — | WO | disclosed |