SCHEMBL304950

SCHEMBL304950

CCCCN(CCCC)C(=O)OC

nearest known ligand 0.52

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CA1 P00915 4/20 0.52
CA12 O43570 4/20 0.52
CA9 Q16790 3/20 0.52
MMP1 P03956 1/20 0.48
MMP2 P08253 1/20 0.48
MMP3 P08254 1/20 0.48
MMP8 P22894 1/20 0.48
ALDH1A1 P00352 1/20 0.41
ALDH2 P05091 1/20 0.41
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2D6 P10635 1/20 0.39
CYP2C19 P33261 1/20 0.39
ACHE P22303 6/20 0.39
EPHX1 P07099 3/20 0.39
CA2 P00918 2/20 0.39
CA14 Q9ULX7 1/20 0.37
ALOX15 P16050 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7956550 0.93 CA12 (0.45) CA1CA12CA9MMP1MMP2
SCHEMBL25278347 0.91 CA12 (0.47) CA1CA12CA9MMP1MMP2
SCHEMBL31105843 0.91 CA12 (0.47) CA1CA12CA9MMP1MMP2
SCHEMBL16091402 0.91 CA12 (0.55) CA1CA12CA9MMP1MMP2
SCHEMBL25227711 0.91 CA12 (0.47) CA1CA12CA9MMP1MMP2
SCHEMBL25227867 0.91 CA12 (0.47) CA1CA12CA9MMP1MMP2
SCHEMBL25227059 0.91 CA12 (0.47) CA1CA12CA9MMP1MMP2
SCHEMBL25224503 0.91 CA12 (0.47) CA1CA12CA9MMP1MMP2
SCHEMBL7954410 0.91 CA12 (0.47) CA1CA12CA9MMP1MMP2
SCHEMBL3973653 0.90 CA12 (0.44) CA1CA12CA9MMP1MMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7687490-B2 2-thioethenyl substituted carbapenem derivatives MEIJI SEIKA KAISHA, LTD. (JP) 2010-03-30 US claimed
EP-1870412-A1 2-THIOETHENYL CARBAPENEM DERIVATIVE MEIJI SEIKA KAISHA LTD. (JP) 2007-12-26 EP claimed
US-20070004700-A1 2-Thioethenyl substituted carbapenem derivatives MEIJI SEIKA KAISHA, LTD. (JP) 2007-01-04 US claimed
EP-4446310-A1 METHOD FOR PRODUCING BLOCKED ISOCYANATE COMPOUND AND METHOD FOR PRODUCING ISOCYANATE COMPOUND Asahi Kasei Kabushiki Kaisha (JP) 2024-10-16 EP disclosed
CN-118382612-A Method for producing blocked isocyanate compound and method for producing isocyanate compound 旭化成株式会社 2024-07-23 CN disclosed
WO-2023106377-A1 METHOD FOR PRODUCING BLOCKED ISOCYANATE COMPOUND AND METHOD FOR PRODUCING ISOCYANATE COMPOUND 旭化成株式会社 2023-06-15 WO disclosed
CN-104813231-B Photo-hardening composition, transfer materials, hardening thing and its manufacturing method, resin pattern manufacturing method, cured film and its application 富士胶片株式会社 2018-12-04 CN disclosed
CN-104317164-B Black curable composition 富士胶片株式会社 2018-03-30 CN disclosed
US-20160151322-A1 METALLO-B-LACTAMASE INHIBITORS MEIJI SEIKA KAISHA (JP) 2016-06-02 US disclosed
US-9260375-B2 Metallo-β-lactamase inhibitors MEIJI SEIKA KAISHA, LTD. (JP) 2016-02-16 US disclosed
EP-2415875-B1 METHOD FOR IDENTIFICATION OF METALLO-[BETA]-LACTAMASE-PRODUCING BACTERIUM MEIJI SEIKA PHARMA CO LTD (JP) 2015-11-04 EP disclosed
US-20070004700-A1 2-Thioethenyl substituted carbapenem derivatives MEIJI SEIKA KAISHA, LTD. (JP) 2007-01-04 US disclosed
US-6245779-B1 ANALGESICS; ANTIINFLAMMATORY AGENTS OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) 2001-06-12 US disclosed
EP-0997463-A1 NAPHTHYRIDINE DERIVATIVES OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) 2000-05-03 EP disclosed
US-4621149-A PLATINUM GROUP METAL HALOGEN OR HALOGEN COMPOUND ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1986-11-04 US disclosed
EP-0083096-A2 Production of urethane compounds Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1983-07-06 EP disclosed
EP-0000352-B1 CYCLIC AROMATIC DIESTERS OF PHOSPHONOUS ACID AND THE ORGANIC MATERIALS STABILIZED BY THEM CIBA-GEIGY AG (CH) 1982-05-05 EP disclosed
US-4276232-A FOR PLASTICS AND ELASTOMERS CIBA-GEIGY CORPORATION (US) 1981-06-30 US disclosed
EP-0000354-A1 Mixtures that contain phosphonite, and polymers stabilized therewith CIBA-GEIGY AG (CH) 1979-01-24 EP disclosed
EP-0000352-A1 Cyclic aromatic diesters of phosphonous acid and the organic materials stabilized by them CIBA-GEIGY AG (CH) 1979-01-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070004700-A1 2-Thioethenyl substituted carbapenem derivatives MTAP, BLVRB, BPGM CA1 3160/4885CA12 799/4885CA9 765/4885
US-20160151322-A1 METALLO-B-LACTAMASE INHIBITORS ME1, MGAM, MANBA CA1 921/4885CA12 953/4885CA9 163/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.