SCHEMBL304982

SCHEMBL304982

O=C1OC(Br)c2ccccc21

nearest known ligand 0.53

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.53
MEN1 O00255 1/20 0.39
POLB P06746 1/20 0.39
KMT2A Q03164 1/20 0.39
HSD17B10 Q99714 3/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA9 Q16790 1/20 0.39
NPC1 O15118 1/20 0.39
ALOX15 P16050 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
KDM4E B2RXH2 3/20 0.38
GAA P10253 1/20 0.38
LMNA P02545 1/20 0.37
TP53 P04637 1/20 0.37
MAPT P10636 1/20 0.37
HTT P42858 1/20 0.37
GFER P55789 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12991705 1.00 ALDH1A1 (0.53) ALDH1A1MEN1POLBKMT2AHSD17B10
SCHEMBL10542289 1.00 ALDH1A1 (0.53) ALDH1A1MEN1POLBKMT2AHSD17B10
SCHEMBL29791776 0.78 ALDH1A1 (0.59) ALDH1A1MEN1POLBKMT2AHSD17B10
SCHEMBL86917 0.75 S100A4 (0.42) ALDH1A1MEN1KMT2ACA1CA2
SCHEMBL17075818 0.75 CYP1A2 (0.47) MEN1KMT2ACA1CA2CA9
SCHEMBL29440609 0.75 CYP1A2 (0.47) MEN1KMT2ACA1CA2CA9
SCHEMBL29440612 0.75 CYP1A2 (0.47) MEN1KMT2ACA1CA2CA9
SCHEMBL4820959 0.74 ALDH1A1 (0.55) ALDH1A1MEN1POLBKMT2AHSD17B10
SCHEMBL25314868 0.74 MAOB (0.36) CA1CA2CA9KDM4E
SCHEMBL10534353 0.74 ALDH1A1 (0.59) ALDH1A1MEN1KMT2AHSD17B10CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 479 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4570901-A1 METHOD FOR SELECTIVE REMOVAL OF UNDIFFERENTIATED PLURIPOTENT STEM CELLS Buddhist Tzu Chi Medical Foundation (TW) 2025-06-18 EP claimed
CN-120137900-A Method for selectively removing undifferentiated pluripotent stem cells 佛教慈济医疗财团法人 2025-06-13 CN claimed
US-20250188411-A1 METHOD FOR SELECTIVE REMOVAL OF UNDIFFERENTIATED PLURIPOTENT STEM CELLS BUDDHIST TZU CHI MEDICAL FOUNDATION (TW) 2025-06-12 US claimed
CN-116041295-B Preparation method of 3-bromophthalide 寿光祥铭化工有限公司 2023-06-06 CN claimed
CN-110698411-B 4- (aminoalkyl) phthalazine-1-ketone compound, preparation method and application thereof 四川大学 2023-05-09 CN claimed
CN-114805263-B 3- (hydroxybenzyl) phthalide compound, preparation method and application thereof 四川大学 2023-05-05 CN claimed
CN-116041295-A Preparation method of 3-bromophthalide 寿光祥铭化工有限公司 2023-05-02 CN claimed
CN-104788414-A Synthetic method of butylphthalide JINAN CHENGHUI SHUANGDA CHEMICAL CO LTD 2015-07-22 CN claimed
CN-104496949-A Preparation method of 3-bromophthalide TAICANG YUNTONG BIOCHEMICAL ENGINEERING CO LTD 2015-04-08 CN claimed
CN-104447303-A Preparation technology of carboxybenzaldehyde TAICANG YUNTONG BIOCHEMICAL ENGINEERING CO LTD 2015-03-25 CN claimed
CN-101735041-B Preparation method of 2-carboxybenzaldehyde TAICANG YUNTONG CHEMICAL FACTORY 2013-06-12 CN claimed
CN-101735041-A Preparation method of 2-carboxybenzaldehyde TAICANG YUNTONG CHEMICAL FACTO 2010-06-16 CN claimed
EP-1327630-B1 NEW DERIVATIVES OF CYANO-ARYL (OR CYANOHETEROARYL)-CARBONYL-PIPERAZINYL-PYRIMIDINES, THEIR PREPARATION AND APPLICATION AS MEDICATION ESTEVE LABOR DR (ES) 2007-12-12 EP claimed
US-7300937-B2 Derivatives of cyano-aryl (or cyanoheteroaryl)-carbonyl-piperazinyl-pyrimidines, their preparation and application as medication LABORATORIOS DEL DR. ESTEVE, S.A. (ES) 2007-11-27 US claimed
US-20040048872-A1 New derivatives of cyano-aryl (or cyanoheteroaryl) -carbonyl- piperazinyl - pyrimidines, their preparation and application as medication LABORATORIES DEL DR. ESTEVE, S.A. (ES) 2004-03-11 US claimed
EP-1327630-A1 NEW DERIVATIVES OF CYANO-ARYL (OR CYANOHETEROARYL)-CARBONYL-PIPERAZINYL-PYRIMIDINES, THEIR PREPARATION AND APPLICATION AS MEDICATION LABORATORIOS DEL DR. ESTEVE, S.A. (ES) 2003-07-16 EP claimed
EP-0025838-B1 PROCESS FOR PREPARING 3-BROMOPHTHALIDE HÜLS TROISDORF AKTIENGESELLSCHAFT (DE) 1982-12-15 EP claimed
US-4211710-A Process of preparing 3-bromophthalide DYNAMIT NOBEL AKTIENGESELLSCHAFT (DE) 1980-07-08 US claimed
JP-4264088-A None JP disclosed
US-3951954-A Novel oxofuryl ester derivatives of penicillin and cephalosporin YAMANOUCHI PHARMACEUTICAL CO., LTD. (JA) 1976-04-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040048872-A1 New derivatives of cyano-aryl (or cyanoheteroaryl) -carbonyl- piperazinyl - pyrimidines, their preparation and application as medication CBR3, CBR1, CNR1 ALDH1A1 304/4885MEN1 4664/4885POLB 2115/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.