Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29791776 | 0.80 | ALDH1A1 (0.59) | ALDH1A1MEN1POLBKMT2AHSD17B10 | |
| SCHEMBL13329531 | 0.74 | ALDH1A1 (0.53) | ALDH1A1MEN1POLBKMT2AHSD17B10 | |
| SCHEMBL12991705 | 0.74 | ALDH1A1 (0.53) | ALDH1A1MEN1POLBKMT2AHSD17B10 | |
| SCHEMBL14019428 | 0.74 | ALDH1A1 (0.53) | ALDH1A1MEN1POLBKMT2AHSD17B10 | |
| SCHEMBL6770346 | 0.74 | ALDH1A1 (0.53) | ALDH1A1MEN1POLBKMT2AHSD17B10 | |
| SCHEMBL3037795 | 0.74 | ALDH1A1 (0.53) | ALDH1A1MEN1POLBKMT2AHSD17B10 | |
| SCHEMBL868796 | 0.74 | ALDH1A1 (0.53) | ALDH1A1MEN1POLBKMT2AHSD17B10 | |
| SCHEMBL2668143 | 0.74 | ALDH1A1 (0.53) | ALDH1A1MEN1POLBKMT2AHSD17B10 | |
| SCHEMBL10542289 | 0.74 | ALDH1A1 (0.53) | ALDH1A1MEN1POLBKMT2AHSD17B10 | |
| SCHEMBL304982 | 0.74 | ALDH1A1 (0.53) | ALDH1A1MEN1POLBKMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 180 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2497475-A1 | Treatment of laminitis with platelet aggregation inhibitors | Dussler, Sabine (DE) | 2012-09-12 | — | — | EP | claimed |
| EP-1562903-A4 | MUCIN SYNTHESIS INHIBITORS | GENAERA CORP (US) | 2006-09-20 | — | — | EP | claimed |
| EP-1562903-A2 | MUCIN SYNTHESIS INHIBITORS | Genaera Corporation (US) | 2005-08-17 | — | — | EP | claimed |
| WO-2004043392-A2 | MUCIN SYNTHESIS INHIBITORS | GENAERA CORPORATION (US) | 2004-05-27 | — | — | WO | claimed |
| US-20030236220-A1 | MUCIN SYNTHESIS INHIBITORS | GENAERA CORPORATION (US) | 2003-12-25 | — | — | US | claimed |
| US-5994356-A | ANTICOAGULANT | KARL THOMAE (DE) | 1999-11-30 | — | — | US | claimed |
| EP-0809626-B1 | PRODUCTION OF ENANTIOMERICALLY ENRICHED ORTHO-SUBSTITUTED ALPHA, ALPHA DIAROMATIC METHANOLS | NOVARTIS AG (CH) | 1999-09-01 | — | — | EP | claimed |
| EP-0542411-B1 | TETRAHYDROTHIENOPYRIDINE DERIVATIVES, FURO AND PYRROLO ANALOGS THEREOF AND THEIR PREPARATION AND USES FOR INHIBITING BLOOD PLATELET AGGREGATION | SANKYO CO (JP) | 1998-08-12 | — | — | EP | claimed |
| US-5700801-A | ANTIINFLAMMATORY AGENTS, BONE DISORDERS | KARL THOMAE, GMBH (DE) | 1997-12-23 | — | — | US | claimed |
| EP-0809626-A1 | PRODUCTION OF ENANTIOMERICALLY ENRICHED ORTHO-SUBSTITUTED $g(a),$g(a)-DIAROMATIC METHANOLS | Novartis AG (CH) | 1997-12-03 | — | — | EP | claimed |
| US-4410520-A | ANGIOTENSION CONVERTING ENZYME INGIBITOR, HYPOTENSIVE AGENTS | CIBA-GEIGY CORPORATION (US) | 1983-10-18 | — | — | US | claimed |
| EP-0003960-B1 | 6-SUBSTITUTED THIA-AZA-COMPOUNDS, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | CIBA-GEIGY AG (CH) | 1983-06-29 | — | — | EP | claimed |
| EP-0082113-A1 | 2-Aminobytyl-2-penem derivatives, process for their preparation and pharmaceutical compositions containing them | CIBA-GEIGY AG (CH) | 1983-06-22 | — | — | EP | claimed |
| EP-0072352-A1 | Benzazepin-2-ones, process for their preparation, pharmaceutical preparations containing these compounds and the compounds for therapeutical use | CIBA-GEIGY AG (CH) | 1983-02-16 | — | — | EP | claimed |
| WO-1982003860-A1 | DERIVATIVES OF 1,4-THIAZANE-CARBOXYLIC ACID,PREPARATION AND UTILIZATION THEREOF AND COMPOSITIONS CONTAINING SAME | GILLET CLAUDE | 1982-11-11 | — | — | WO | claimed |
| EP-0061765-A1 | Beta-Lactams | E.R. SQUIBB & SONS, INC. (US) | 1982-10-06 | — | — | EP | claimed |
| US-4301279-A | Process for the production of 3-hydroxy compounds | CIBA-GEIGY CORPORATION (US) | 1981-11-17 | — | — | US | claimed |
| US-4293462-A | Process for the manufacture of enol derivatives, and intermediates | CIBA-GEIGY CORPORATION (US) | 1981-10-06 | — | — | US | claimed |
| US-4232151-A | ANTIBIOTICS | SHIONOGI & CO., LTD. (JP) | 1980-11-04 | — | — | US | claimed |
| EP-0003960-A1 | 6-Substituted thia-aza-compounds, their preparation and pharmaceutical compositions containing them | CIBA-GEIGY AG (CH) | 1979-09-19 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030236220-A1 | MUCIN SYNTHESIS INHIBITORS | MUC1, CFTR, SERPINB1 | ALDH1A1 1261/4885MEN1 3719/4885POLB 2310/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.