Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HAO1 | Q9UJM8 | 7/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 4/20 | 0.34 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29068124 | 0.73 | HAO1 (0.42) | HAO1FFAR1BACE1GRM5FFAR4 | |
| SCHEMBL6209834 | 0.70 | — | — | |
| SCHEMBL27160636 | 0.69 | ALDH2 (0.37) | NOTUMGRM5 | |
| SCHEMBL1027196 | 0.69 | — | — | |
| SCHEMBL21333512 | 0.69 | — | — | |
| SCHEMBL29417247 | 0.67 | PTGES (0.42) | HAO1FFAR1BACE1GRM5 | |
| SCHEMBL4941651 | 0.63 | GRM5 (0.55) | FFAR1GRM5 | |
| SCHEMBL4210103 | 0.62 | HAO1 (0.50) | HAO1FFAR1GRM5 | |
| SCHEMBL28619044 | 0.61 | ALDH1A1 (0.51) | FFAR1P2RY6 | |
| SCHEMBL15322825 | 0.61 | ALDH1A1 (0.41) | FFAR1BACE1P2RY6TBK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116669727-A | Triazole-pyridinyl substituted azacyclohexylacetic acid compounds as LPA receptor antagonists | 唯久生物有限公司 | 2023-08-29 | — | — | CN | disclosed |