⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6209834 | 0.79 | — | — | |
| SCHEMBL21333512 | 0.77 | — | — | |
| SCHEMBL2671435 | 0.69 | ATIC (0.60) | — | |
| SCHEMBL3574426 | 0.69 | IMPDH2 (0.58) | — | |
| SCHEMBL28489960 | 0.69 | GRM5 (0.64) | — | |
| SCHEMBL30500463 | 0.69 | HAO1 (0.38) | — | |
| Hydrochloric Acid SCHEMBL7004520 | 0.67 | GRM5 (0.62) | — | |
| SCHEMBL6042142 | 0.67 | NOTUM (0.77) | — | |
| SCHEMBL9199411 | 0.65 | — | — | |
| SCHEMBL91366 | 0.65 | IMPDH2 (1.00) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110263610-A1 | COMPOUNDS AND COMPOSITIONS AS ITPKB INHIBITORS | IRM LLC (BM) | 2011-10-27 | — | — | US | claimed |
| EP-4685143-A1 | DOUBLE REGULATOR FOR MGLUR5 AND HDAC6 AND USE THEREOF | Vivozon,Inc. (KR) | 2026-01-28 | — | — | EP | disclosed |
| US-12312345-B2 | Fluoroalkyl-oxadiazoles and uses thereof | TENAYA THERAPEUTICS, INC. (US) | 2025-05-27 | — | — | US | disclosed |
| US-20250092040-A1 | AKT1 MODULATORS | ALTEROME THERAPEUTICS, INC. | 2025-03-20 | — | — | US | disclosed |
| WO-2025011476-A1 | INDAZOLE DERIVATIVE OR PHARMACEUTICAL SALT THEREOF AND USE THEREOF | 浙江大学 | 2025-01-16 | — | — | WO | disclosed |
| CN-119219609-A | Indazole derivative or pharmaceutically acceptable salt thereof and application thereof | 浙江大学 | 2024-12-31 | — | — | CN | disclosed |
| WO-2024196136-A1 | DOUBLE REGULATOR FOR MGLUR5 AND HDAC6 AND USE THEREOF | 주식회사 비보존 | 2024-09-26 | — | — | WO | disclosed |
| US-20240239797-A1 | AKT1 MODULATORS | ALTEROME THERAPEUTICS, INC. | 2024-07-18 | — | — | US | disclosed |
| US-20240239797-A1 | AKT1 MODULATORS | ALTEROME THERAPEUTICS, INC. | 2024-07-18 | — | — | US | disclosed |
| US-20240228469-A1 | PCSK9 INHIBITORS AND METHODS OF USE THEREOF | ASTRAZENECA AB (SE) | 2024-07-11 | — | — | US | disclosed |
| US-20110034697-A1 | PROCESS FOR PREPARING 2-HYDROXY-4-SUBSTITUTED PYRIDINES | YUKI GOSEI KOGYO CO., INC. (JP) | 2011-02-10 | — | — | US | disclosed |
| US-20110027864-A1 | PROCESS FOR PREPARING 2-HYDROXY-4-SUBSTITUTED PYRIDINES | YUKI GOSEI KOGYO CO., INC. (JP) | 2011-02-03 | — | — | US | disclosed |
| EP-2274302-A2 | COMPOUNDS AND COMPOSITIONS AS ITPKB INHIBITORS | IRM LLC (BM) | 2011-01-19 | — | — | EP | disclosed |
| US-7803585-B2 | Process for preparing 2-Hydroxy-4-Substituted Pyridines | YUKI GOSEI KOGYO CO., LTD. (JP) | 2010-09-28 | — | — | US | disclosed |
| EP-1959951-B1 | HETEROARYL SUBSTITUTED PIPERIDINE DERIVATIVES AS L-CPT1 INHIBITORS | HOFFMANN LA ROCHE (CH) | 2009-12-23 | — | — | EP | disclosed |
| WO-2009123948-A2 | COMPOUNDS AND COMPOSITIONS AS ITPKB INHIBITORS | IRM LLC (BM) | 2009-10-08 | — | — | WO | disclosed |
| CN-101321525-A | Heteroaryl substituted piperidine derivatives as L-CPT1 inhibitors | HOFFMANN LA ROCHE (CH) | 2008-12-10 | — | — | CN | disclosed |
| US-20080286843-A1 | Process for Preparing 2-Hydroxy-Substituted Pyridines | YUKI GOSEI KOGYO CO., INC. (JP) | 2008-11-20 | — | — | US | disclosed |
| WO-2007075783-A2 | SUBSTITUTED ISOQUINOLINE-1,3(2H,4H)-DIONES, 1-THIOXO-1,4-DIHYDRO-2H-ISOQUINOLINE-3-ONES AND 1,4-DIHYDRO-3(2H)-ISOQUINOLONES AND USE THEREOF AS KINASE INHIBITOR | WYETH (US) | 2007-07-05 | — | — | WO | disclosed |
| EP-1801102-A1 | PROCESS FOR PRODUCTION OF 2-HYDROXY-4-SUBSTITUTED PYRIDINES | YUKI GOSEI KOGYO CO., LTD. (JP) | 2007-06-27 | — | — | EP | disclosed |