SCHEMBL30500513

SCHEMBL30500513

CCc1ccc(-c2ccccc2)c(CC)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.53
ALDH1A1 P00352 1/20 0.53
LMNA P02545 1/20 0.53
MAPT P10636 1/20 0.53
MAPK1 P28482 1/20 0.53
RAB9A P51151 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
CYP1A2 P05177 1/20 0.45
CYP2A6 P11509 1/20 0.45
TP53 P04637 1/20 0.44
FOLH1 Q04609 1/20 0.42
BCL2 P10415 1/20 0.42
CSNK2A1 P68400 3/20 0.42
DPP4 P27487 1/20 0.41
CSNK2A2 P19784 1/20 0.40
CSNK2B P67870 1/20 0.40
CSNK2A3 Q8NEV1 1/20 0.40
PDK2 Q15119 1/20 0.39
KMT2A Q03164 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4662861 0.89 FOLH1 (0.44) NPC1ALDH1A1LMNAMAPTMAPK1
SCHEMBL4664590 0.87 ALDH1A1 (0.41) NPC1ALDH1A1LMNAMAPTMAPK1
SCHEMBL19824469 0.85 TDP1 (0.45) NPC1ALDH1A1LMNAMAPTMAPK1
SCHEMBL7169867 0.84 MAPT (0.53) NPC1ALDH1A1LMNAMAPTMAPK1
SCHEMBL19194181 0.84 ALDH1A1 (0.39) NPC1ALDH1A1LMNAMAPTMAPK1
SCHEMBL9978839 0.84 TSHR (0.55) ALDH1A1LMNAMAPTFOLH1
SCHEMBL8459740 0.83 MAPT (0.57) NPC1ALDH1A1LMNAMAPTMAPK1
SCHEMBL9618333 0.82 SMN1; SMN2 (0.47) NPC1LMNAMAPTRAB9ASMN1; SMN2
SCHEMBL1483731 0.81 ALDH1A1 (0.42) NPC1ALDH1A1LMNAMAPTMAPK1
SCHEMBL28252223 0.81 HSD17B1 (0.45) NPC1ALDH1A1LMNAMAPTMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117296468-A Composition for organic electroluminescent element, display device, and lighting device 三菱化学株式会社 2023-12-26 CN disclosed
CN-116670252-A Composition for organic electroluminescent element, display device, and lighting device 三菱化学株式会社 2023-08-29 CN disclosed