Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDXK | O00764 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.37 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.36 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 4/20 | 0.32 |
| ▸ | PLAU | P00749 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16177071 | 1.00 | PDXK (0.50) | PDXKKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL15413206 | 0.77 | PDXK (0.44) | PDXKKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL1961170 | 0.71 | PLAU (0.33) | PDXKALDH1A1PLAU | |
| SCHEMBL4920949 | 0.71 | PDXK (0.46) | PDXKKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL31395900 | 0.71 | PDXK (0.46) | PDXKKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL30032050 | 0.71 | RECQL (0.39) | PDXKKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL5742153 | 0.71 | RECQL (0.39) | PDXKKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL15211577 | 0.71 | PDXK (0.46) | PDXKKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL6664399 | 0.70 | PLAU (0.44) | KDM4EALDH1A1PLAU | |
| SCHEMBL29047829 | 0.70 | NOS3 (0.41) | PDXKALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113024547-B | Bicyclic heterocycles as FGFR4 inhibitors | 因赛特控股公司 | 2023-07-21 | — | — | CN | disclosed |