SCHEMBL30500681

SCHEMBL30500681

O=c1c2nc(Br)n([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)c2nc2[nH]ccn12

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PNP P00491 1/20 0.44
▸ NADK O95544 1/20 0.41
▸ MAPT P10636 2/20 0.41
▸ CYP3A4 P08684 1/20 0.41
▸ CYP1A2 P05177 1/20 0.41
▸ MEN1 O00255 1/20 0.39
▸ KMT2A Q03164 1/20 0.39
▸ HSPA5 P11021 1/20 0.39
▸ HSPA8 P11142 1/20 0.39
▸ HPGD P15428 1/20 0.39
▸ LMNA P02545 1/20 0.39
▸ THRB P10828 1/20 0.39
▸ MTOR P42345 1/20 0.39
▸ MDM2 Q00987 1/20 0.39
▸ NCOA1 Q15788 1/20 0.39
▸ NCOA3 Q9Y6Q9 1/20 0.39
▸ TDP1 Q9NUW8 1/20 0.39
▸ CDA P32320 1/20 0.38
▸ PYGM P11217 1/20 0.38
▸ PAX8 Q06710 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4858272 0.80 HPGD (0.59) HPGDLMNAPAX8
SCHEMBL30500723 0.79 CYP1A2 (0.46) NADKMAPTCYP3A4CYP1A2MEN1
SCHEMBL20547890 0.74 ADORA2A (0.55) HPGDLMNAPAX8
SCHEMBL14941501 0.73 PNP (0.79) PNPNADKMAPTCYP3A4MEN1
SCHEMBL56019 0.73 PNP (0.79) PNPNADKMAPTCYP3A4MEN1
SCHEMBL23202308 0.73 PNP (0.79) PNPNADKMAPTCYP3A4MEN1
SCHEMBL10117789 0.73 PNP (0.79) PNPNADKMAPTCYP3A4MEN1
SCHEMBL2774442 0.73 PNP (0.79) PNPNADKMAPTCYP3A4MEN1
SCHEMBL12746818 0.73 PNP (0.79) PNPNADKMAPTCYP3A4MEN1
SCHEMBL12030980 0.73 PNP (0.79) PNPNADKMAPTCYP3A4MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230242568-A1 POLYMER LINKED MULTIMERS OF GUANOSINE-3', 5'-CYCLIC MONOPHOSPHATES MIRECA MEDICINES GMBH (DE) 2023-08-03 — — US claimed
US-12384813-B2 Polymer linked multimers of guanosine-3′, 5′-cyclic monophosphates MIRECA MEDICINES GMBH (DE) 2025-08-12 — — US disclosed
US-20230242568-A1 POLYMER LINKED MULTIMERS OF GUANOSINE-3', 5'-CYCLIC MONOPHOSPHATES MIRECA MEDICINES GMBH (DE) 2023-08-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230242568-A1 POLYMER LINKED MULTIMERS OF GUANOSINE-3', 5'-CYCLIC MONOPHOSPHATES PRKG1, PRKG2, PRKAG3 PNP 111/4885NADK 788/4885MAPT 4120/4885
US-12384813-B2 Polymer linked multimers of guanosine-3′, 5′-cyclic monophosphates PRKG1, PRKG2, PRKAG3 PNP 107/4885NADK 780/4885MAPT 4139/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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