Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | FGB | P02675 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL995102 | 0.91 | CA1 (0.46) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL30501017 | 0.81 | PTGS2 (0.42) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL16810770 | 0.77 | KCNQ2 (0.42) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL14191206 | 0.76 | CA1 (0.50) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL30501016 | 0.75 | MEN1 (0.55) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL30833582 | 0.75 | MEN1 (0.55) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL357510 | 0.75 | MEN1 (0.55) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL16766189 | 0.75 | PDK2 (0.45) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL995711 | 0.75 | SMN1; SMN2 (0.46) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL16810788 | 0.74 | PDK2 (0.49) | MEN1KMT2AMAPTKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116462579-B | Preparation method of spirofluorene anthrone compound | 大连理工大学 | 2024-04-05 | — | — | CN | disclosed |
| CN-116462579-A | Preparation method of spirofluorene anthrone compound | 大连理工大学 | 2023-07-21 | — | — | CN | disclosed |