SCHEMBL30501286

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL25333582	1.00	HRH3 (0.40)	HRH3HTR2ACYP2D6SLC6A2SLC6A4
	SCHEMBL25935225	0.74	CRBN (0.43)	—
	SCHEMBL30501237	0.73	HRH3 (0.38)	HRH3HTR2ACYP2D6SLC6A2SLC6A4
	SCHEMBL25332809	0.73	HRH3 (0.38)	HRH3HTR2ACYP2D6SLC6A2SLC6A4
	SCHEMBL10162463	0.72	PDE3B (0.44)	HRH3
	SCHEMBL30479004	0.71	GRM2 (0.35)	HRH3HTR2ACYP2D6SLC6A2SLC6A4
	SCHEMBL24127250	0.70	CYP2D6 (0.54)	HTR2ACYP2D6SLC6A2SLC6A4SLC6A3
	SCHEMBL31342725	0.67	DRD2 (0.38)	HTR2ACYP2D6SLC6A2SLC6A4SLC6A3
	SCHEMBL31342612	0.67	GRM2 (0.41)	HTR2ACYP2D6SLC6A2SLC6A4SLC6A3
	SCHEMBL31342200	0.67	DRD2 (0.41)	HTR2ACYP2D6SLC6A2SLC6A4SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.